Redox metals in Alzheimer's disease

被引:46
|
作者
Todorich, BM [1 ]
Connor, JR [1 ]
机构
[1] Penn State Univ, Sch Med, George M Leader Family Lab Alzheimers Dis Res, Dept Neural & Behav Sci, Hershey, PA 17033 USA
关键词
Alzheimer's disease (AD); redox metal; iron; copper; zinc; brain;
D O I
10.1196/annals.1306.014
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Redox metals in the brain play many important roles in maintenance of cellular function. The maintenance of their homeostasis is of paramount importance to a number of diseases such as Alzheimer's disease and multiple sclerosis. Iron, copper, and zinc are metals of special interest in the pathogenesis of these disorders. This review will focus primarily on iron.
引用
收藏
页码:171 / 178
页数:8
相关论文
共 50 条
  • [1] Redox active metals In Alzheimer's disease
    Dey, Somdatta Ghosh
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [2] Redox-active metals, oxidative stress, and Alzheimer's disease pathology
    Huang, XD
    Moir, RD
    Tanzi, RE
    Bush, AI
    Rogers, JT
    REDOX-ACTIVE METALS IN NEUROLOGICAL DISORDERS, 2004, 1012 : 153 - 163
  • [3] Metals in Alzheimer's Disease
    Leko, Mirjana Babic
    Horvat, Lea Langer
    Popovacki, Ena Spanic
    Zubcic, Klara
    Hof, Patrick R.
    Simic, Goran
    BIOMEDICINES, 2023, 11 (04)
  • [4] Metals and Alzheimer's disease
    Adlard, Paul A.
    Bush, Ashley I.
    JOURNAL OF ALZHEIMERS DISEASE, 2006, 10 (2-3) : 145 - 163
  • [5] Role of metals in Alzheimer's disease
    Das, Nikita
    Raymick, James
    Sarkar, Sumit
    METABOLIC BRAIN DISEASE, 2021, 36 (07) : 1627 - 1639
  • [6] Metals in Alzheimer's disease - Foreword
    Miu, Andrei C.
    Benga, Oana
    JOURNAL OF ALZHEIMERS DISEASE, 2006, 10 (2-3) : 133 - 133
  • [7] Metals in Imaging of Alzheimer's Disease
    Krasnovskaya, Olga
    Spector, Daniil
    Zlobin, Alexander
    Pavlov, Kirill
    Gorelkin, Peter
    Erofeev, Alexander
    Beloglazkina, Elena
    Majouga, Alexander
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (23) : 1 - 35
  • [8] Role of metals in Alzheimer’s disease
    Nikita Das
    James Raymick
    Sumit Sarkar
    Metabolic Brain Disease, 2021, 36 : 1627 - 1639
  • [9] Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis
    Plascencia-Villa, German
    Perry, George
    ANTIOXIDANTS & REDOX SIGNALING, 2021, 34 (08) : 591 - 610
  • [10] Redox signaling and metabolism in Alzheimer's disease
    Holubiec, M. I.
    Gellert, M.
    Hanschmann, E. M.
    FRONTIERS IN AGING NEUROSCIENCE, 2022, 14