Alpha-Klotho in Parkinson's disease: a perspective on experimental evidence and potential clinical implications

被引:7
作者
Grillo, Piergiorgio [1 ]
Basilicata, Michele [2 ]
Schirinzi, Tommaso [1 ]
机构
[1] Univ Roma Tor Vergata, Dept Syst Med, Neurol Unit, Rome, Italy
[2] Univ Roma Tor Vergata, Dept Expt Med & Surg, Rome, Italy
关键词
D O I
10.4103/1673-5374.335820
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:2687 / 2688
页数:2
相关论文
共 14 条
[1]   The anti-aging protein klotho alleviates injury of nigrostriatal dopaminergic pathway in 6-hydroxydopamine rat model of Parkinson's disease: Involvement of PKA/CaMKII/CREB signaling [J].
Baluchnejadmojarad, Tourandokht ;
Eftekhari, Seyed-Mohammad ;
Jamali-Raeufy, Nida ;
Haghani, Sobhan ;
Zeinali, Hossein ;
Roghani, Mehrdad .
EXPERIMENTAL GERONTOLOGY, 2017, 100 :70-76
[2]   Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4 [J].
Belloy, Michael E. ;
Napolioni, Valerio ;
Han, Summer S. ;
Le Guen, Yann ;
Greicius, Michael D. ;
Initiative, Alzheimer's Disease Neuroimaging .
JAMA NEUROLOGY, 2020, 77 (07) :849-862
[3]   Salivary alpha-synuclein as a biomarker for Parkinson's disease: a systematic review [J].
Bougea, Anastasia ;
Koros, Christos ;
Stefanis, Leonidas .
JOURNAL OF NEURAL TRANSMISSION, 2019, 126 (11) :1373-1382
[4]   Inflammatory Bowel Diseases and Parkinson's Disease [J].
Brudek, Tomasz .
JOURNAL OF PARKINSONS DISEASE, 2019, 9 :S331-S344
[5]   Klotho: An Elephant in Aging Research [J].
Cheikhi, Amin ;
Barchowsky, Aaron ;
Sahu, Amrita ;
Shinde, Sunita N. ;
Pius, Abish ;
Clemens, Zachary J. ;
Li, Hua ;
Kennedy, Charles A. ;
Hoeck, Joerg D. ;
Franti, Michael ;
Ambrosio, Fabrisia .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2019, 74 (07) :1031-1042
[6]   Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study [J].
Horsager, Jacob ;
Andersen, Katrine B. ;
Knudsen, Karoline ;
Skjaerbaek, Casper ;
Fedorova, Tatyana D. ;
Okkels, Niels ;
Schaeffer, Eva ;
Bonkat, Sarah K. ;
Geday, Jacob ;
Otto, Marit ;
Sommerauer, Michael ;
Danielsen, Erik H. ;
Bech, Einar ;
Kraft, Jonas ;
Munk, Ole L. ;
Hansen, Sandra D. ;
Pavese, Nicola ;
Goeder, Robert ;
Brooks, David J. ;
Berg, Daniela ;
Borghammer, Per .
BRAIN, 2020, 143 :3077-3088
[7]   Peripheral Klotho and Parkinson's Disease [J].
Kakar, Rumit S. ;
Pastor, Johanne V. ;
Moe, Orson W. ;
Ambrosio, Fabrisia ;
Castaldi, Danielle ;
Sanders, Laurie H. .
MOVEMENT DISORDERS, 2021, 36 (05) :1274-1276
[8]   Degeneration of mesencephalic dopaminergic neurons in klotho mouse related to vitamin D exposure [J].
Kosakai, Arifumi ;
Ito, Daisuke ;
Nihei, Yoshihiro ;
Yamashita, Shuji ;
Okada, Yasunori ;
Takahashi, Kazushi ;
Suzuki, Norihiro .
BRAIN RESEARCH, 2011, 1382 :109-117
[9]   Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice [J].
Leon, Julio ;
Moreno, Arturo J. ;
Garay, Bayardo I. ;
Chalkley, Robert J. ;
Burlingame, Alma L. ;
Wang, Dan ;
Dubal, Dena B. .
CELL REPORTS, 2017, 20 (06) :1360-1371
[10]   Soluble klotho regulates the function of salivary glands by activating KLF4 pathways [J].
Nguyen Chi Tai ;
Kim, Soo-A ;
Ahn, Sang-Gun .
AGING-US, 2019, 11 (19) :8254-8269