New Method for the Synthesis and Reactivity of (5-R-1,3,4-Oxadiazol-2-yl)furoxans

被引：18

作者：

Fershtat, Leonid L. ^{[1
]}

Kulikov, Alexander S. ^{[1
]}

Ananyev, Ivan V. ^{[2
]}

Struchkova, Marina I. ^{[1
]}

Makhova, Nina N. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Pr, Moscow 119991, Russia

[2] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, 28 Vavilova St, Moscow 119991, Russia

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2016年 / 53卷 / 01期

关键词：

DERIVATIVES; ACID;

D O I：

10.1002/jhet.1940

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new, simple and general one-pot method for the preparation of (5-R-1,3,4-oxadiazol-2-yl)furoxans has been developed on the basis of the interaction between accessible 3-methylfuroxan-4-carboxylic acid hydrazide and aliphatic, aromatic and heterocyclic carboxylic acids or their chlorides in the presence of POCl3. The synthesis and study of (5-R-1,3,4-oxadiazol-2-yl)furoxans reactivity resulted in new polyheterocyclic ensembles incorporating furoxan, 1,3,4-oxadiazole, pyrrole, triazole, furan, thiophene, pyrimidine, and other heterocycles in different combinations.

引用

页码：102 / 108

页数：7

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