Surgical Management of Crohn Disease in Children: Guidelines From the Paediatric IBD Porto Group of ESPGHAN

被引：70

作者：

Amil-Dias, Jorge ^{[1
]}

Kolacek, Sanja ^{[2
]}

Turner, Dan ^{[3
]}

Paerregaard, Anders ^{[4
]}

Rintala, Risto ^{[5
]}

Afzal, Nadeem A. ^{[6
]}

Karolewska-Bochenek, Katarzyna ^{[7
]}

Bronsky, Jiri ^{[8
]}

Chong, Sonny ^{[9
]}

Fell, John ^{[10
]}

Hojsak, Iva ^{[2
]}

Hugot, Jean-Pierre ^{[11
,12
]}

Koletzko, Sibylle ^{[13
]}

Kumar, Devinder ^{[14
]}

Lazowska-Przeorek, Izabella ^{[7
]}

Lillehei, Craig ^{[15
,16
]}

Lionetti, Paolo ^{[17
]}

Martin-de-Carpi, Javier ^{[18
]}

Pakarinen, Mikko ^{[5
]}

Ruemmele, Frank M. ^{[19
]}

Shaoul, Ron ^{[20
]}

Spray, Christine ^{[21
]}

Staiano, Annamaria ^{[22
]}

Sugarman, Ian ^{[23
]}

Wilson, David C. ^{[24
]}

Winter, Harland ^{[25
]}

Kolho, Kaija-Leena ^{[26
]}

机构：

[1] Ctr Hosp S Joao, Dept Pediat, P-4202451 Oporto, Portugal

[2] Childrens Hosp Zagreb, Fac Med, Zagreb, Croatia

[3] Hebrew Univ Jerusalem, Juliet Keidan Inst Pediat Gastroenterol & Nutr, Shaare Zedek Med Ctr, Jerusalem, Israel

[4] Hvidovre Univ Hosp, Dept Pediat, Hvidovre, Denmark

[5] Univ Helsinki, Childrens Hosp, Pediat Surg, Helsinki, Finland

[6] Univ Hosp Southampton, Dept Pediat Gastroenterol, Southampton, Hants, England

[7] Med Univ Warsaw, Dept Pediat Gastroenterol & Nutr, Warsaw, Poland

[8] Univ Hosp Motol, Dept Pediat, Prague, Czech Republic

[9] Queen Marys Hosp Children, Epsom & St Helier NHS Trust, Surrey, England

[10] Chelsea & Westminster Hosp, London, England

[11] Paris Diderot Sorbonne Paris Cite Univ, Paris, France

[12] Robert Debre Hosp, Paris, France

[13] Ludwig Maximilians Univ Munchen, Dr von Hauner Childrens Hosp, Pediatr Gastroenterol & Hepatol, Munich, Germany

[14] St Georges Univ London, London, England

[15] Boston Childrens Hosp, Boston, MA USA

[16] Harvard Med Sch, Boston, MA USA

[17] Univ Florence, Meyer Hosp, Dept NEUROFARBA, Florence, Italy

[18] Hosp San Juan Dios, Unit Comprehens Care Pediat Inflammatory Bowel Di, Barcelona, Spain

[19] Paris Descartes Univ, Sorbonne Paris Cite Univ,Necker Enfants Malades U, Inst IMAGINE, INSERM U1163,Dept Pediat Gastroenterol, Paris, France

[20] Ruth Childrens Hosp, Rambam Med Ctr, Pediat Gastroenterol Inst, Haifa, Israel

[21] Bristol Royal Hosp Children, Dept Pediat Gastroenterol, Bristol, Avon, England

[22] Univ Naples Federico II, Dept Translat Med Sci, Sect Pediat, Naples, Italy

[23] Leeds Childrens Hosp, Leeds Gen Infirm, Dept Pediat Surg, Leeds, W Yorkshire, England

[24] Univ Edinburgh, Child Life & Hlth, Edinburgh, Midlothian, Scotland

[25] Harvard Med Sch, MassGen Hosp Children, Boston, MA USA

[26] Univ Helsinki, Childrens Hosp, Helsinki, Finland

来源：

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION | 2017年 / 64卷 / 05期

关键词：

biologicals; complications; Crohn disease; inflammatory bowel disease; surgery; treatment; INFLAMMATORY-BOWEL-DISEASE; POUCH-ANAL ANASTOMOSIS; LONG-TERM OUTCOMES; BILE-ACID MALABSORPTION; POSTOPERATIVE ENDOSCOPIC RECURRENCE; INTRAABDOMINAL SEPTIC COMPLICATIONS; OPEN ILEOCOLIC RESECTION; PREOPERATIVE STEROID USE; POPULATION-BASED COHORT; QUALITY-OF-LIFE;

D O I：

10.1097/MPG.0000000000001562

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The incidence of Crohn disease (CD) has been increasing and surgery needs to be contemplated in a substantial number of cases. The relevant advent of biological treatment has changed but not eliminated the need for surgery in many patients. Despite previous publications on the indications for surgery in CD, there was a need for a comprehensive review of existing evidence on the role of elective surgery and options in pediatric patients affected with CD. We present an expert opinion and critical review of the literature to provide evidence-based guidance to manage these patients. Indications, surgical options, risk factors, and medications in pre-and perioperative period are reviewed in the light of available evidence. Risks and benefits of surgical options are addressed. An algorithm is proposed for the management of postsurgery monitoring, timing for follow-up endoscopy, and treatment options.

引用

页码：818 / 835

页数：18

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