Efficient synthesis of 1-substituted-5-hydroxymethylimidazole derivatives: Clean oxidative cleavage of 2-mercapto group

被引：14

作者：

Chang, JH ^{[1
]}

Lee, KW ^{[1
]}

Nam, DH ^{[1
]}

Kim, WS ^{[1
]}

Shin, K ^{[1
]}

机构：

[1] LGCI Ltd, Life Sci R&D, Taejon 305380, South Korea

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2002年 / 6卷 / 05期

关键词：

D O I：

10.1021/op020015c

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

1-Substituted-5-hydroxymethylimidazoles were prepared through green desulfurization of their 2-mercapto derivatives by the treatment of 30% hydrogen peroxide in the presence of a catalytic amount of transition metal catalysts.

引用

页码：674 / 676

页数：3

共 27 条

[1] AMINO Y, 1989, CHEM PHARM BULL, V37, P1481
[2] ANTONINI I, 1983, SYNTHESIS-STUTTGART, P47
[3] ASKIN D, Patent No. 0001674
[4] Preparation and structure determination of 1-benzyl-, 1-methyl- and 1H-5-[(2-nitro-2-phenyl)ethenyl]imidazoles
Aulaskari, P
Ahlgren, M
Rouvinen, J
Vainiotalo, P
Pohjala, E
Vepsalainen, J
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1996, 33 (04) : 1345 - 1354
[5] OXO-PEROXO OXYGEN-EXCHANGE IN PEROXOVANADIUM(V) AND PEROXOMOLYBDENUM(VI) COMPOUNDS
BORTOLINI, O
DIFURIA, F
MODENA, G
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (13) : 3924 - 3926
[6] Mercaptothiazoles: Oxidation and alkylation studies
Buchman, ER
Reims, AO
Sargent, H
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1941, 6 (05) : 764 - 773
[7] THIAZOLETHIOLS AND THEIR DERIVATIVES
DAMICO, JJ
BARTRAM, TW
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1960, 25 (08) : 1336 - 1342
[8] FUTURE GLOBAL WARMING FROM ATMOSPHERIC TRACE GASES
DICKINSON, RE
CICERONE, RJ
[J]. NATURE, 1986, 319 (6049) : 109 - 115
[9] THE PREPARATION OF 2-ALKYLTHIOIMIDAZOLES
DODSON, RM
ROSS, F
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1950, 72 (04) : 1478 - 1480
[10] Francis MB, 1999, ANGEW CHEM INT EDIT, V38, P937, DOI 10.1002/(SICI)1521-3773(19990401)38:7<937::AID-ANIE937>3.0.CO

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