Nonlinear photoacoustic waves for light guiding to deep tissue sites

被引:5
|
作者
Ishijima, Ayumu [1 ]
Yagyu, Ukyo [2 ]
Kitamura, Kenta [3 ]
Tsukamoto, Akira [4 ]
Sakuma, Ichiro [1 ,2 ,3 ]
Nakagawa, Keiichi [2 ,3 ]
机构
[1] Univ Tokyo, Med Device Dev & Regulat Res Ctr, Tokyo 1138656, Japan
[2] Univ Tokyo, Dept Precis Engn, Tokyo 1138656, Japan
[3] Univ Tokyo, Dept Bioengn, Tokyo 1138656, Japan
[4] Natl Def Acad, Dept Appl Phys, Yokosuka, Kanagawa 2398686, Japan
基金
日本学术振兴会;
关键词
PHOTODYNAMIC THERAPY; TIME;
D O I
10.1364/OL.44.003006
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Light scattering by tissues limits performance in biological sensing or stimulation. Here we present a photoacoustic technique that increases light transmittance by one order of magnitude and enables light localization in deep tissue. Laser-induced nonlinear acoustic waves are utilized to produce a high refractive index contrast in scattering medium without high-intensity pressure. The size of guiding area is around 60 mu m, which is equivalent or smaller than the diameter of multimode fibers. To show potential use in biomedical fields, we performed light guiding and imaging of fluorescence, through swine tissues with thickness more than 1 mm. (C) 2019 Optical Society of America
引用
收藏
页码:3006 / 3009
页数:4
相关论文
共 50 条
  • [31] LIGHT WAVES MIXING IN NONLINEAR ANISOTROPIC MEDIA
    SOLIMINI, D
    PROCEEDINGS OF THE IEEE, 1963, 51 (11) : 1408 - +
  • [32] Waves of polarized light in nonlinear birefringent fibre
    Elyutin, SO
    Maimistov, AI
    CHAOS SOLITONS & FRACTALS, 2000, 11 (08) : 1253 - 1259
  • [33] INTERACTIONS BETWEEN LIGHT WAVES IN A NONLINEAR DIELECTRIC
    ARMSTRONG, JA
    BLOEMBERGEN, N
    DUCUING, J
    PERSHAN, PS
    PHYSICAL REVIEW, 1962, 127 (06): : 1918 - +
  • [34] Nonlinear induced reflection of light waves in semiconductors
    A. F. Bunkin
    V. G. Mikhalevich
    S. M. Pershin
    V. N. Streltsov
    Physics of Wave Phenomena, 2016, 24 : 279 - 281
  • [35] Deep-tissue photoacoustic tomography of Forster resonance energy transfer
    Wang, Yu
    Xia, Jun
    Wang, Lihong V.
    JOURNAL OF BIOMEDICAL OPTICS, 2013, 18 (10)
  • [36] Photoacoustic Design Parameter Optimization for Deep Tissue Imaging by Numerical Simulation
    Wang, Zhaohui
    Ha, Seunghan
    Kim, Kang
    PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2012, 2012, 8223
  • [37] Recent Advances in Photoacoustic Imaging for Deep-Tissue Biomedical Applications
    Wang, Sheng
    Lin, Jing
    Wang, Tianfu
    Chen, Xiaoyuan
    Huang, Peng
    THERANOSTICS, 2016, 6 (13): : 2394 - 2413
  • [38] Spectroscopic Imaging of Deep Tissue through Photoacoustic Detection of Molecular Vibration
    Wang, Pu
    Rajian, Justin R.
    Cheng, Ji-Xin
    JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2013, 4 (13): : 2177 - 2185
  • [39] Deep tissue photoacoustic computed tomography with a fast and compact laser system
    Wang, Depeng
    Wang, Yuehang
    Wang, Weiran
    Luo, Dandan
    Chitgupi, Upendra
    Geng, Jumin
    Zhou, Yang
    Wang, Lidai
    Lovell, Jonathan F.
    Xia, Jun
    BIOMEDICAL OPTICS EXPRESS, 2017, 8 (01): : 112 - 123
  • [40] Evaluation of Microvasculature Diameter in Deep Tissue Using a Photoacoustic Spectral Analysis
    Gao, Xiaoxiang
    Tao, Chao
    Liu, Xiaojun
    Wang, Xueding
    2015 OPTO-ELECTRONICS AND COMMUNICATIONS CONFERENCE (OECC), 2015,