Thin-layer chromatography: A neglected technique

被引：18
|
作者：
Wilson, ID
机构：
来源：
THERAPEUTIC DRUG MONITORING | 1996年 / 18卷 / 04期
关键词：
thin-layer chromatography; high-performance thin-layer chromatography; quantitative analysis; identification;
D O I：
10.1097/00007691-199608000-00030
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Thin-layer(or planar) chromatography (TLC) is critically reviewed from the point of view of drug analysis in biological fluids. The capabilities of the various techniques of TLC are described and their advantages and disadvantages are discussed. An example of the use of high-performance TLC with scanning densitometry for the quantitative determination of antipyrine in human plasma is provided. The use of TLC-mass spectrometry and TLC-tandem mass spectrometry, directly from the sorbent, in the identification of the compounds separated by TLC is discussed.
引用
收藏
页码：484 / 492
页数：9
相关论文
共 50 条
  • [31] Quantification of Metal Dithiocarbamates by Thin-Layer Chromatography
    Zakrzewski, Robert
    Rembisz, Zaneta
    Ciesielski, Witold
    Celichowski, Grzegorz
    JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC, 2013, 26 (06) : 502 - 507
  • [32] IDENTIFICATION OF CORTICOSTEROID HORMONES BY THIN-LAYER CHROMATOGRAPHY
    HOEBUS, J
    DANEELS, E
    ROETS, E
    HOOGMARTENS, J
    JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC, 1993, 6 (04) : 269 - 273
  • [33] Thin-layer chromatography in the analysis of surfactants: At a glance
    Mohammad, Ali
    Qasimullah
    Khan, Mahfoozurrahman
    Mobin, Rizwana
    JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2017, 40 (17) : 863 - 871
  • [34] Quantification of Metal Dithiocarbamates by Thin-Layer Chromatography
    Robert Zakrzewski
    Żaneta Rembisz
    Witold Ciesielski
    Grzegorz Celichowski
    JPC – Journal of Planar Chromatography – Modern TLC, 2013, 26 : 502 - 507
  • [35] Microemulsion in Chemical Analyses by Thin-Layer Chromatography
    Ali Qasimullah
    Mahfoozurrahman Mohammad
    JPC – Journal of Planar Chromatography – Modern TLC, 2017, 30 : 7 - 16
  • [36] Thin-layer chromatography of phenolic acids on aminopropylsilica
    Wojciak-Kosior, Magdalena
    Skalska, Agnieszka
    JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC, 2006, 19 (109) : 200 - 203
  • [37] Thin-Layer Chromatography of Phenolic Acids on Aminopropylsilica
    Magdalena Wójciak-Kosior
    Agnieszka Skalska
    JPC – Journal of Planar Chromatography – Modern TLC, 2006, 19 : 200 - 203
  • [38] THIN-LAYER CHROMATOGRAPHY ANALYSIS OF PHOTOCOPY TONERS
    TANDON, G
    JASUJA, OP
    SEHGAL, VN
    FORENSIC SCIENCE INTERNATIONAL, 1995, 73 (02) : 149 - 154
  • [39] Determination of cortisol in guinea pig urine by high performance thin-layer chromatography, high performance liquid chromatography, and thin-layer chromatography/radioimmunoassay
    M. Fenske
    Chromatographia, 1997, 44 : 50 - 54
  • [40] SORBENTS FOR THIN-LAYER CHROMATOGRAPHY IN PHARMACEUTICAL ANALYSIS
    Goroshko, O. A.
    Checha, O. A.
    Pakhomov, V. P.
    Ruvinov, Yu. V.
    Ismagilov, T. D.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2010, 44 (09) : 521 - 524
12345