A brief personal account of a journey in science - an interview with Alejandro Sanchez-Alvarado

被引:0
作者
Garcia-Arraras, Jose E. [1 ]
Sanchez-Alvarado, Alejandro [1 ]
机构
[1] Univ Puerto Rico, Dept Biol, Rio Piedras, PR USA
关键词
Venezuela; planaria; regeneration; developmental biology; STEM-CELLS; SCHMIDTEA-MEDITERRANEA; TISSUE HOMEOSTASIS; GENE-EXPRESSION; REGENERATION; TURNOVER;
D O I
10.1387/ijdb.200043jg
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Alejandro Sanchez Alvarado represents a younger generation of Latin American scientists that have achieved international scientific recognition. His work, together with that from other labs, has positioned the planaria Schmidtea mediterranea as a dynamic model system in which the cellular and molecular bases of regeneration in metazoans can be probed. During his professional career he has established strong ties with Latin America, hosting and training students and participating in seminars, workshops and courses throughout the region. In this interview he discusses his early scientific development and training, and his views on various issues related to the professional development of young scientists.
引用
收藏
页码:137 / 141
页数:5
相关论文
共 19 条
[1]   To solve old problems, study new research organisms [J].
Alvarado, Alejandro Sanchez .
DEVELOPMENTAL BIOLOGY, 2018, 433 (02) :111-114
[2]  
Alvarado AS, 2000, BIOESSAYS, V22, P578, DOI 10.1002/(SICI)1521-1878(200006)22:6<578::AID-BIES11>3.0.CO
[3]  
2-#
[4]   Regeneration and the need for simpler model organisms [J].
Alvarado, AS .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2004, 359 (1445) :759-763
[5]   The freshwater planarian Schmidtea mediterranea:: embryogenesis, stem cells and regeneration -: Commentary [J].
Alvarado, AS .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 2003, 13 (04) :438-444
[6]   Double-stranded RNA specifically disrupts gene expression during planarian regeneration [J].
Alvarado, AS ;
Newmark, PA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (09) :5049-5054
[7]   Pathogenic shifts in endogenous microbiota impede tissue regeneration via distinct activation of TAK1/MKK/p38 [J].
Arnold, C. P. ;
Merryman, M. S. ;
Harris-Arnold, A. ;
McKinney, S. A. ;
Seidel, C. W. ;
Loethen, S. ;
Proctor, K. N. ;
Guo, L. ;
Alvarado, Sanchez A. .
ELIFE, 2016, 5
[8]   Wnt and TGFβ coordinate growth and patterning to regulate size-dependent behaviour [J].
Arnold, Christopher P. ;
Benham-Pyle, Blair W. ;
Lange, Jeffrey J. ;
Wood, Christopher J. ;
Alvarado, Alejandro Sanchez .
NATURE, 2019, 572 (7771) :655-+
[9]   Regulation of Genomic Output and (Pluri)potency in Regeneration [J].
Duncan, Elizabeth M. ;
Alvarado, Alejandro Sanchez .
ANNUAL REVIEW OF GENETICS, VOL 53, 2019, 53 :327-346
[10]   β-catenin defines head versus tail identity during planarian regeneration and Homeostasis [J].
Gurley, Kyle A. ;
Rink, Jochen C. ;
Alvarado, Alejandro Sanchez .
SCIENCE, 2008, 319 (5861) :323-327