Heat shock proteins, tumor immunogenicity and antigen presentation: an integrated view

被引：127
作者：
Wells, AD [1 ]
Malkovsky, M
机构：
[1] Univ Penn, Dept Med, Philadelphia, PA 19104 USA
[2] Univ Wisconsin, Sch Med, Ctr Comprehens Canc, Dept Med Microbiol & Immunol, Madison, WI 53706 USA
[3] Univ Wisconsin, Wisconsin Reg Primate Res Ctr, Madison, WI 53706 USA
来源：
IMMUNOLOGY TODAY | 2000年 / 21卷 / 03期
关键词：
D O I：
10.1016/S0167-5699(99)01558-3
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A broad range of studies has established that heat shock proteins (Hsps) potentially play a role,in tumor immunosurveillance. Here, Andrew Wells and Miroslav, Malkovsky highlight recent data that demonstrate a causal relationship between the expression of Hsps and tumor immunogenicity, and suggest several mechanisms by which Hsps might influence the capacity of a tumor to induce nn immune response.
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收藏
页码：129 / 132
页数：4
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