Fluorescent Carbon Dots for Bioimaging and Biosensing Applications

被引：106

作者：

Shi, Haitang ^{[1
,2
]}

Wei, Jianfei ^{[1
,2
]}

Qiang, Li ^{[1
,2
]}

Chen, Xue ^{[1
,2
]}

Meng, Xianwei ^{[1
]}

机构：

[1] Chinese Acad Sci, Tech Inst Phys & Chem, Lab Controllable Preparat & Applicat Nanomat, Beijing 100190, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

来源：

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY | 2014年 / 10卷 / 10期

基金：

中国国家自然科学基金;

关键词：

Carbon Dots; Fluorescence; Nanoparticles; Bioimaging; Biosensing; STEP GREEN SYNTHESIS; GRAPHENE QUANTUM DOTS; TIO2 NANOTUBE ARRAYS; BOVINE SERUM-ALBUMIN; LABEL-FREE DETECTION; ONE-POT SYNTHESIS; SELECTIVE DETECTION; VISIBLE-LIGHT; SENSITIVE DETECTION; TURN-ON;

D O I：

10.1166/jbn.2014.1881

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Due to the excellent biocompatibility, carbon dots (CDs), which are attracting considerable attention as new quantum-sized carbon-containing fluorescent nanoparticles, are becoming both an important class of imaging probes and a versatile platform for biosensors. In the process of transferring carbon dots from proof-of-concept studies to real bioimaging and biosensing applications, major advances have already been made in their synthesis, structure, properties, mechanism of fluorescence, and evaluation of biocompatibility and bio-applications. This review aims to summarize the recent developments and trends in carbon dots. Investigations of preparation methods, fluorescent properties and applications as biosensors and in bioimaging for carbon dots are described. In addition, this review highlights on the design and construct of a carbon dot fluorescent ratiometric biosensing platform for the detection of enzymatic activity, substrate and inhibitor concentrations related to the production or consumption of H2O2. This review provides perspectives on future opportunities and the remaining challenges confronting this research field.

引用

页码：2677 / 2699

页数：23

共 199 条

[61] Carbon nanodots: synthesis, properties and applications [J].