Apoptosis: Telling cells their time is up

被引：71

作者：

Nagata, S ^{[1
]}

机构：

[1] OSAKA BIOSCI INST,SUITA,OSAKA 565,JAPAN

来源：

CURRENT BIOLOGY | 1996年 / 6卷 / 10期

关键词：

D O I：

10.1016/S0960-9822(02)70706-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ligand engagement by the receptor Fas leads to apoptosis. A clue to how this happens comes from the discovery that ligand binding leads to recruitment to Fas of a protease, homologous to interleukin-1 beta converting enzyme, likely to initiate a proteolytic cascade that drives apoptosis.

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页码：1241 / 1243

页数：3

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