Pseudomonas aeruginosa outbreak associated with a contaminated blood-gas analyser in a neonatal intensive care unit

被引:29
作者
Garland, SM
Mackay, S
Tabrizi, S
Jacobs, S
机构
[1] ROYAL WOMENS HOSP,NURSING DIV,CARLTON,VIC 3053,AUSTRALIA
[2] ROYAL WOMENS HOSP,PAEDIAT DIV,CARLTON,VIC 3053,AUSTRALIA
关键词
Pseudomonas aeruginosa; blood-gas analyser; neonates; sepsis; DNA fingerprinting;
D O I
10.1016/S0195-6701(96)90099-7
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Over a 10 month period in a neonatal intensive care unit there was an outbreak of infection caused by Pseudomonas aeruginosa (resistant to ticarcillin, timentin) which involved 24 newborns. There was extensive morbidity and mortality (38%) associated with the infections, which presented as septicaemia (N=6) (five succumbed and four had coexisting pneumonia), pneumonia (N=6), meningitis (one, died), conjunctivitis (N=1), otitis externa (N=1), conjunctivitis plus otitis externa (N=1). In addition there were two pseudosepticaemias and six colonized infants, three of whom were treated for the presence of P. aeruginosa in endotracheal aspirates. There was always at least one baby colonized or infected with P. aeruginosa during the outbreak. Environmental surveillance and genomic DNA fingerprinting of isolates identified the blood gas analyser port as the likely reservoir for the outbreak. Further spread of the organism did not occur after commencement of staff education on vigilant and careful handwashing, especially after use of the blood-gas analyser.
引用
收藏
页码:145 / 151
页数:7
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