Analysis of gene expression during development: Lessons from the Apicomplexa

被引:18
作者
Boyle, Jon P. [1 ]
Saeij, Jeroen P. J. [1 ]
Cleary, Michael D. [1 ]
Boothroyd, John C. [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Immunol & Microbiol, Stanford, CA 94305 USA
关键词
microarray analysis; malaria; toxoplasmosis; host-parasite relationship; histone deacetylases;
D O I
10.1016/j.micinf.2005.11.017
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Apicomplexans are responsible for significant human and animal disease worldwide, including malaria and toxoplasmosis. Herein we summarize recent advances in gene expression analysis in these eukaryotic pathogens, especially with respect to their developmental biology, and discuss the impact this work may have on the development of new vaccines and chemotherapeutics. (c) 2006 Elsevier SAS. All rights reserved.
引用
收藏
页码:1623 / 1630
页数:8
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