[1] Fac Med, Lab Pharmacol Med, INSERM U766, F-63001 Clermont Ferrand, France
[2] Pfizer Global Res & Dev, Fresnes Labs, Fresnes, France
[3] Univ Clermont 1, Fac Med, Pharmacol Lab, Clermont Ferrand, France
[4] Univ Clermont 1, IUT Biol, Clermont Ferrand, France
[5] CHU Clermont Ferrand, Serv Pharmacol, Hop G Montpied, Clermont Ferrand, France