Two new compounds from the aerial parts of Stelleropsis tianschanica and their cytotoxic activity

被引：1

作者：

Yao, Cai-Hong ^{[1
,2
]}

Sha, Xiao-Song ^{[3
]}

Song, Hai-Long ^{[2
]}

Chen, Gang ^{[2
]}

Ma, Xiao-Ling ^{[2
]}

Shi, Lei-Ling ^{[2
]}

Wei, Hong-Yan ^{[2
]}

机构：

[1] Xinjiang Univ, Coll Life Sci & Technol, Urumqi 830049, Peoples R China

[2] Xinjiang Inst Chinese & Ethn Med, Urumqi 830002, Peoples R China

[3] Shenzhen Univ, Dept Neurosurg, Shenzhen Key Lab Neurosurg, Affiliated Hosp 1,Shenzhen Second Peoples Hosp, 3002 Sungang Rd, Shenzhen 518035, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2021年 / 42卷

关键词：

Stelleropsis; Stelleropsis tianschanica; Neolignan; Diterpenes; Cytotoxic activity; CONSTITUENTS; DIARYLHEPTANOIDS; NEOLIGNANS; LIGNANS; ROOTS;

D O I：

10.1016/j.phytol.2020.09.009

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new components, stelltian A (1) and stelltian B (2), along with two known compounds, neoboutomannin (3) and 6,9-O-dedimethyltrigonostemone (4), were isolated from the aerial parts of Stelleropsis tianschanica. Their structures were clarified using 1D and 2D NMR spectroscopic methods and the HRESIMS spectra. All the isolated compounds were profiled for their antitumor activities against human breast cancer cells (MCF-7) and HeLa cells. Among them, compounds 2?4 have a moderate cytotoxic activity.

引用

页码：134 / 137

页数：4

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