Galactosylated cucurbituril-inclusion polyplex for hepatocyte-targeted gene delivery

被引:60
作者
Kim, Soo Kyung [3 ]
Park, Kyeng Min [1 ,2 ]
Singha, Kaushik [3 ]
Kim, Jeeyeon [1 ,2 ]
Ahn, Youngjoo [1 ,2 ]
Kim, Kimoon [1 ,2 ]
Kim, Won Jong [3 ]
机构
[1] Pohang Univ Sci & Technol POSTECH, Natl Creat Res Initiat, Ctr Smart Supramol, Dept Chem, Pohang 790784, South Korea
[2] Pohang Univ Sci & Technol POSTECH, Div Adv Mat Sci, Pohang 790784, South Korea
[3] Pohang Univ Sci & Technol POSTECH, Dept Chem, Polymer Res Inst, Program BK21, Pohang 790784, South Korea
关键词
TRANSFECTION; THERAPY; DISEASE; COMPLEX; DNA;
D O I
10.1039/b920753h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The work demonstrates a judicious approach to achieve hepatocyte cell-targeted highly efficient gene delivery by utilizing a supramolecular complex of galactosylated cucurbituril and dextran-spermine conjugates.
引用
收藏
页码:692 / 694
页数:3
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