Apoptosis in ischemic heart disease

被引：204
作者：
Teringova, Elena [1 ,2 ]
Tousek, Petr [1 ,2 ]
机构：
[1] Charles Univ Prague, Dept Cardiol, Fac Med 3, Cardioctr, Srobarova 50, Prague 10034 10, Czech Republic
[2] Univ Hosp Kralovske Vinohrady, Srobarova 50, Prague 10034 10, Czech Republic
来源：
JOURNAL OF TRANSLATIONAL MEDICINE | 2017年 / 15卷
关键词：
Apoptosis; Ischemic heart disease; Outcome; Heart failure; TUMOR-NECROSIS-FACTOR; ACUTE MYOCARDIAL-INFARCTION; FACTOR-ALPHA THERAPY; SOLUBLE FAS; PROGNOSTIC VALUE; BCL-2; PROTEIN; PLASMA-LEVELS; SERUM-LEVELS; CELL-DEATH; FAILURE;
D O I：
10.1186/s12967-017-1191-y
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Apoptosis plays an important role in the myocardial loss after acute myocardial infarction and participates in the process of subsequent left ventricular remodeling and development of symptomatic heart failure. Finding a sensitive apoptotic marker that would help in prognostic stratification of patients after acute myocardial infarction and offer new therapeutic strategies is thus of a great importance. Several studies suggest that tumor necrosis factor-related apoptosis inducing ligand (TRAIL) represents a very promising marker of prognosis in patients with acute myocardial infarction. This review article provides an overview of current knowledge on the role of apoptosis in ischemic heart disease and highlights potentially beneficial apoptotic markers in clinical practice.
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页数：7
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共 66 条
  • [1] Increased myocardial apoptosis in patients with unfavorable left ventricular remodeling and early symptomatic post-infarction heart failure
    Abbate, A
    Biondi-Zoccai, GGL
    Bussani, R
    Dobrina, A
    Camilot, D
    Feroce, F
    Rossiello, R
    Baldi, F
    Silvestri, F
    Biasucci, LM
    Baldi, A
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 41 (05) : 753 - 760
  • [2] Abbate A, 2000, Clin Ter, V151, P247
  • [3] Serum Caspase-3 p17 Fragment Is Elevated in Patients With ST-Segment Elevation Myocardial Infarction A Novel Observation
    Agosto, Mariela
    Azrin, Michael
    Singh, Kanwar
    Jaffe, Allan S.
    Liang, Bruce T.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2011, 57 (02) : 220 - 221
  • [4] An Immunohistochemistry Study of Tissue Bcl-2 Expression and Its Serum Levels in Breast Cancer Patients
    Alireza, Andalib
    Raheleh, Shokohi
    Abbass, Rezaei
    Mojgan, Mokhtari
    Mohamadreza, Mohageri
    Gholamreza, Mohageri
    Shadi, Babazadeh
    [J]. RECENT ADVANCES IN CLINICAL ONCOLOGY, 2008, 1138 : 114 - 120
  • [5] Do TNF Inhibitors Reduce the Risk of Myocardial Infarction in Psoriasis Patients?
    Armstrong, April W.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 309 (19): : 2043 - 2044
  • [6] Dual effects of tumor necrosis factor alpha on myocardial injury following prolonged hypoperfusion of the heart
    Asgeri, Mehrdad
    Pourafkari, Leili
    Kundra, Amita
    Javadzadegan, Hassan
    Negargar, Sohrab
    Nader, Nader D.
    [J]. IMMUNOLOGICAL INVESTIGATIONS, 2015, 44 (01) : 23 - 35
  • [7] Death receptors: Signaling and modulation
    Ashkenazi, A
    Dixit, VM
    [J]. SCIENCE, 1998, 281 (5381) : 1305 - 1308
  • [8] Apoptosis and post-infarction left ventricular remodeling
    Baldi, A
    Abbate, A
    Bussani, R
    Patti, G
    Melfi, R
    Angelini, A
    Dobrina, A
    Rossiello, R
    Silvestri, F
    Baldi, F
    Di Sciascio, G
    [J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2002, 34 (02) : 165 - 174
  • [9] Systematic Review and Meta-Analysis: Anti-Tumor Necrosis Factor α Therapy and Cardiovascular Events in Rheumatoid Arthritis
    Barnabe, Cheryl
    Martin, Billie-Jean
    Ghali, William A.
    [J]. ARTHRITIS CARE & RESEARCH, 2011, 63 (04) : 522 - 529
  • [10] The role of apoptosis in normal and abnormal embryonic development
    Brill, A
    Torchinsky, A
    Carp, H
    Toder, V
    [J]. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 1999, 16 (10) : 512 - 519
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