A Case of Galactorrhea Associated with Excitalopram

被引：15
作者：
Shim, Se-Hoon [1 ]
Lee, Yeon-Jeong [1 ]
Lee, Eun-Chan [2 ]
机构：
[1] Soonchunhyang Univ, Coll Med, Cheonan Hosp, Dept Psychiat, Cheonan 330721, South Korea
[2] DANA Hosp, Ansan, South Korea
来源：
PSYCHIATRY INVESTIGATION | 2009年 / 6卷 / 03期
关键词：
Escitalopram; Depression; Prolactin; Galactorrhea; Side effect; SERUM PROLACTIN; FLUOXETINE; NEURONS;
D O I：
10.4306/pi.2009.6.3.230
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Escitalopram is one of the most popular selective serotonin reuptake inhibitors (SSRIs) in current use as a first-line treatment for depression. Escitalopram is well-tolerated and rarely associated with serious side effects. Endocrine and reproductive side effects of serotonergic antidepressants are uncommon and galactorrhea is very rarely mentioned among SSRI-related side effects. Serotonin-enhancing antidepressants may result in a rise in prolactin levels through suppression of dopamine neurotransmission. In the present study, we report a case of hyperprolactinemic galactorrhea associated with escitalopram. A 36-year-old woman developed galactorrhea after initiation of escitalopram for depression and was found to have an elevated prolactin level. Escitalopram was discontinued with resolution of the patient's galactorrhea and normalization of her prolactin level.
引用
收藏
页码：230 / 232
页数：3
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