Preparation and characteristics of sodium alginate/Nerectorite-g-itaconic acid/acrylamide hydrogel films

被引：13

作者：

Yang, Lianli ^{[1
]}

Ma, Xiaoyan ^{[2
]}

Guo, Naini ^{[1
]}

Zhang, Yang ^{[1
]}

机构：

[1] Xianyang Normal Univ, Coll Chem & Chem Engn, Xianyang 712000, Shaanxi, Peoples R China

[2] Northwestern Polytech Univ, Sch Sci, Dept Appl Chem, Xian 710072, Peoples R China

来源：

CARBOHYDRATE POLYMERS | 2014年 / 105卷

基金：

中国国家自然科学基金;

关键词：

SA/Na+REC-g-IA/AM; Hydrogel film; Preparation; Characteristics; Salicylic acid; Controlled release; DYE ADSORPTION; RECTORITE; ALGINATE; CHITOSAN; ACID; MICROSPHERES; THICKNESS; MEMBRANES; DELIVERY; MATRICES;

D O I：

10.1016/j.carbpol.2014.01.043

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Sodium alginate/Na(+)rectorite-graft-itaconic acid/acrylamide (SA/Na+REC-g-IA/AM) hydrogel film was prepared via solution polymerization. The effect of Na+REC, KPS, and NMBA content and the ratio of IA to AM on graft ratio, graft efficiency and absorption of liquids were investigated. The structure and morphology were analyzed by FTIR, XRD, TEM and SEM. Results revealed that the optimal Na+REC, KPS, and NMBA content and the ratio of IA to AM were 2 wt%, 0.8 wt%, 0.38 wt% and 4, respectively. The hydrogel film was found to exhibit an intercalative structure and coarse surface. The mechanism of graft copolymerization was discussed. A slower and more continuous release of salicylic acid for SA/Na+REC-g-IA/AM composite hydrogel film was shown in vitro drug-controlled release studies, in comparison with SA film. The salicylic acid release mechanism of SA/Na+REC-g-IA/AM hydrogel film followed Fickian diffusion. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：351 / 358

页数：8

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