Synthesis, Characterization, and Antibacterial Activity of Copper(II) Oxide Nanoparticles Prepared by Thermal Decomposition

In the present work, copper(II) oxide nanoparticles were prepared using simple and low-cost from calcination of CuSO4 or Cu(OAC)(2) at the presence of polyvinyl alcohol (PVA) in a weight ratio of 1 : 1 at 600 degrees C for 3 h. The basic properties of CuO nanoparticles were described by Fourier Transform Infrared (FT-IR) spectroscopy, powder X-ray diffraction (XRD) and transmission electron microscopy (TEM). All results confirmed that the as-prepared copper(II) oxide nanoparticles were pure with high degree of crystallinity and that resulting shape, size and morphology of nanoparticles were depending on the applied precursor. In addition, the antibacterial activity of CuO-1 and CuO-2 nanoparticles was performed on Gram-negative E. coli and P. aeruginosa using disc diffusion method cultures throughout at 24 h period. Antibacterial results demonstrated that the as-prepared CuO nanoparticles act as effective bacterial agents.