Oleic Acid Amides With Potential Pharmacological Effects in the Overweight Treatment

被引：0

作者：

Negut, Catalina ^{[1
]}

Pintilie, Lucia ^{[1
]}

Tanase, Constantin ^{[1
]}

Udeanu, Denisa Ioana ^{[2
]}

Draghici, Constantin ^{[3
]}

Munteanu, Cristian ^{[4
]}

Morosan, Elena ^{[2
]}

机构：

[1] Natl Inst Chem Pharmaceut Res & Dev, 112 Vitan Av, Bucharest 031299, Romania

[2] Univ Med & Pharm Carol Davila, Fac Pharm, Dept Clin Lab & Food Safety, 6 Traian Vuia Str, Bucharest 020956, Romania

[3] Organ Chem Ctr CD Nenitescu, 202B Splaiul Independentei, Bucharest 060023, Romania

[4] Romanian Acad Inst Biochem IBAR, 296 Splaiul Independentei, Bucharest 060031, Romania

来源：

REVISTA DE CHIMIE | 2018年 / 69卷 / 04期

关键词：

Fatty acid amide analogues; H-1- and C-13-NMR; IR; MS spectra; food-intake; body weight regulation; ENDOCANNABINOID SYSTEM; OLEAMIDE ANALOGS; FOOD-INTAKE; FATTY; AMIDATION; MECHANISM; CATALYST; SENSORS; CANCER;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fatty acid amide analogues were synthesized from oleic acid, activated by 1,1'-carbonildiimidazole to oleoylimidazole and amines, and characterized by IR, MS, H-1- and C-13-NMR spectra. The compounds were investigated for their influence on body weight and food-intake effects on an obesity-induced mouse model.

引用

页码：790 / 794

页数：5

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