A New and Facile Synthesis of Quinazoline-2,4(1H,3H)-diones

被引：71

作者：

Li Jiarong ^{[1
]}

Chen Xian ^{[1
]}

Shi Daxin ^{[1
]}

Ma Shuling ^{[1
]}

Li Qing ^{[1
]}

Zhang Qi ^{[1
]}

Tang Jianhong ^{[1
]}

机构：

[1] Beijing Inst Technol, Sch Chem Engn & Environm, Beijing 100081, Peoples R China

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 06期

关键词：

CARBON-DIOXIDE; ORTHO-AMINONITRILES; CATALYTIC AMOUNT; O-AMINONITRILES; DERIVATIVES; EFFICIENT; 2,4(1H,3H)-QUINAZOLINEDIONES; 4(3H)-QUINAZOLINONES; QUINAZOLINES; ISOCYANATES;

D O I：

10.1021/ol900093h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl2 (0.5-10 mol %) at 190-200 degrees C in the sealed reactor.

引用

页码：1193 / 1196

页数：4

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