Opioid induced nausea and vomiting

被引：107
作者：
Smith, Howard S. [1 ]
Laufer, Andras [1 ]
机构：
[1] Albany Med Coll, Dept Anesthesiol, Albany, NY 12208 USA
来源：
EUROPEAN JOURNAL OF PHARMACOLOGY | 2014年 / 722卷
关键词：
Nausea; Vomiting; Opioids; Olanzapine; NK-1; Antagonists; Moxduo; Tapentadol; CHEMOTHERAPY-INDUCED NAUSEA; PREVENTING POSTOPERATIVE NAUSEA; TAPENTADOL IMMEDIATE-RELEASE; DORSAL MOTOR NUCLEUS; PHASE-II TRIAL; LOW-BACK-PAIN; DOUBLE-BLIND; TRANSDERMAL SCOPOLAMINE; EXTENDED-RELEASE; RECEPTOR AGONIST;
D O I：
10.1016/j.ejphar.2013.09.074
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Opioids are broad spectrum analgesics that are an integral part of the therapeutic armamentarium to combat pain in the palliative care population. Unfortunately, among the adverse effects of opioids that may be experienced along with analgesia is nausea, vomiting, and/or retching. Although it is conceivable that in the future, using combination agents (opioids combined with agents which may nullify emetic effects), currently nausea/vomiting remains a significant issue for certain patients. However, there exists potential current strategies that may be useful in efforts to diminish the frequency and/or intensity of opioid-induced nausea/vomiting (OINV). Published by Elsevier B.V.
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收藏
页码：67 / 78
页数：12
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