Peripheral muscle dysfunction in chronic obstructive pulmonary disease

被引:0
作者
Maltais, F [1 ]
Leblanc, R [1 ]
Jobin, J [1 ]
Casaburi, R [1 ]
机构
[1] Univ Laval, Hop Laval, Inst Univ Cardiol & Pneumol, Laval, PQ, Canada
关键词
COPD; emphysema; exercise; muscle; oxidative capacity; muscular atrophy;
D O I
暂无
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Patients with chronic obstructive pulmonary disease (COPD) often develop systemic complications of their disease. Peripheral muscle dysfunction is one such complication and is characterised by atrophy, weakness, and low oxidative capacity. These muscle changes influence exercise tolerance and quality of life independent of the impairment in lung function. In the following article, the evidence for peripheral muscle dysfunction in patients with COPD and the possible clinical implications of this problem will be discussed. Lastly, the available therapeutic options to improve peripheral muscle function in COPD will be reviewed.
引用
收藏
页码:444 / 453
页数:10
相关论文
共 60 条
  • [1] [Anonymous], 1999, AM J RESP CRIT CARE, V159, pS1
  • [2] BELMAN MJ, 1981, AM REV RESPIR DIS, V123, P256
  • [3] Aerobic and strength training in patients with chronic obstructive pulmonary disease
    Bernard, S
    Whittom, F
    LeBlanc, P
    Jobin, J
    Belleau, R
    Bérubé, C
    Carrier, G
    Maltais, F
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (03) : 896 - 901
  • [4] Peripheral muscle weakness in patients with chronic obstructive pulmonary-disease
    Bernard, S
    LeBlanc, P
    Whittom, F
    Carrier, G
    Jobin, J
    Belleau, R
    Maltais, F
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 158 (02) : 629 - 634
  • [5] Administration of growth hormone to underweight patients with chronic obstructive pulmonary disease - A prospective, randomized, controlled study
    Burdet, L
    deMuralt, B
    Schutz, Y
    Pichard, C
    Fitting, JW
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1997, 156 (06) : 1800 - 1806
  • [6] Physiologic benefits of exercise training in rehabilitation of patients with severe chronic obstructive pulmonary disease
    Casaburi, R
    Porszasz, J
    Burns, MR
    Carithers, ER
    Chang, RSY
    Cooper, CB
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1997, 155 (05) : 1541 - 1551
  • [7] REDUCTIONS IN EXERCISE LACTIC-ACIDOSIS AND VENTILATION AS A RESULT OF EXERCISE TRAINING IN PATIENTS WITH OBSTRUCTIVE LUNG-DISEASE
    CASABURI, R
    PATESSIO, A
    IOLI, F
    ZANABONI, S
    DONNER, CF
    WASSERMAN, K
    [J]. AMERICAN REVIEW OF RESPIRATORY DISEASE, 1991, 143 (01): : 9 - 18
  • [8] CASABURI R, 1996, AM J RESP CRIT CARE, V153, pA128
  • [9] Peripheral muscle wasting in chronic obstructive pulmonary disease -: Clinical relevance and mechanisms
    Debigarté, R
    Côté, CH
    Maltais, F
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 164 (09) : 1712 - 1717
  • [10] CORTICOSTEROIDS CONTRIBUTE TO MUSCLE WEAKNESS IN CHRONIC AIR-FLOW OBSTRUCTION
    DECRAMER, M
    LACQUET, LM
    FAGARD, R
    ROGIERS, P
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1994, 150 (01) : 11 - 16