[1] IRCCS, Hlth Care Direct, Ist Sci Romagnolo Studio & Cura Tumori IRST, Meldola, Italy
[2] IRCCS, Biostat & Clin Trial Unit, Ist Sci Romagnolo Studio & Cura Tumori IRST, Meldola, Italy
[3] IRCCS, IT Serv, Ist Sci Romagnolo Studio & Cura Tumori IRST, Meldola, Italy
[4] IRCCS, Med Oncol, Ist Sci Romagnolo Studio & Cura Tumori IRST, Meldola, Italy
[5] Merck, CORE Oncol, Rahway, NJ USA
[6] IRCCS, Sci Inst Romagna Study & Treatment Canc IRST, Meldola, Italy