Alkaloids from root bark of Strychnos panganensis

Twelve alkaloids, seven of which are new, have been isolated from the root bark of Strychnos panganensis collected in Tanzania. The known alkaloids are matopensine, 16-(S)-E-isositsirikine, 12-hydroxy-11-methoxydiaboline, N-desacetylretuline and N-desacetylisoretuline. The novel alkaloids are N-desacetylspermostrychnine, 12-hydroxy-11-methoxy-nor-C-fluorocurarine, 12-hydroxy-11-methoxy-N-acetylmon-C-fluorocurarimine and four dimeric alkaloids, panganensines R, S, X and Y. Copyright (C) 1996 Elsevier Science Ltd.