SnapShot: Interferon Signaling

被引：51
作者：
Chow, Kwan T. [1 ]
Gale, Michael, Jr. [1 ]
机构：
[1] Univ Washington, Sch Med, Ctr Innate Immun & Immune Dis, Dept Immunol, Seattle, WA 98109 USA
来源：
CELL | 2015年 / 163卷 / 07期
关键词：
RECEPTOR; STATS;
D O I：
10.1016/j.cell.2015.12.008
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Interferons (IFNs) are crucial cytokines of antimicrobial, antitumor, and immunomodulatory activity. The three types of IFN (I, II, and III) are classified by their receptor specificity and sequence homology. IFNs are produced and secreted by cells in response to specific stimuli. Here, we review the subsequent IFN signaling events occurring through unique receptors leading to regulation of gene expression for modulation of innate and adaptive immunity. To view this SnapShot, open or download the PDF.
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页数：2
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