A systematic review of the comorbidity between PTSD and alcohol misuse

被引:271
作者
Debell, Frances [1 ]
Fear, Nicola T. [2 ,3 ]
Head, Marc [1 ]
Batt-Rawden, Samantha [2 ]
Greenberg, Neil [3 ]
Wessely, Simon [2 ]
Goodwin, Laura [2 ]
机构
[1] Kings Coll London, Sch Med, London SE1 1UL, England
[2] Kings Coll London, Weston Educ Ctr, Kings Ctr Mil Hlth Res, Dept Psychol Med,Inst Psychiat, London SE5 9RJ, England
[3] Kings Coll London, Weston Educ Ctr, Acad Ctr Def Mental Hlth, Dept Psychol Med,Inst Psychiat, London SE5 9RJ, England
关键词
Post-traumatic stress disorder; Alcohol misuse; Alcohol use disorder; Comorbidity; POSTTRAUMATIC-STRESS-DISORDER; HEALTH-CARE-SEEKING; QUALITY-OF-LIFE; SUBSTANCE USE; AFGHANISTAN VETERANS; ANXIETY DISORDERS; MENTAL-HEALTH; PSYCHIATRIC COMORBIDITY; HAZARDOUS DRINKING; GENDER-DIFFERENCES;
D O I
10.1007/s00127-014-0855-7
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
This systematic review aimed to assess (1) the level of comorbidity of post-traumatic stress disorder (PTSD) and alcohol misuse reported in research studies since 2007 and (2) any associations found between specific PTSD symptom clusters and alcohol misuse. A literature search was carried out to capture any papers published from 2007 to the end of July 2012. Six hundred and twenty abstracts were identified and reviewed, and 42 papers were included in the final review after applying inclusion and exclusion criteria. The prevalence of comorbid alcohol misuse in those with PTSD ranged from 9.8 to 61.3 %. The prevalence of comorbid PTSD in those with alcohol misuse ranged from 2.0 to 63.0 %, and the majority of prevalence rates were over 10.0 %. Almost all of the odds ratios representing the strength of association between the conditions across a variety of populations were significant, and those ranged from 1.1 to 4.87. Of the different PTSD symptom clusters, this review found most evidence for associations between alcohol misuse and both avoidance/numbing symptoms and hyperarousal symptoms. Given that comorbidity appears to be common, the evidence from this systematic review supports the use of routine screening for comorbidity in populations who are known to have PTSD or alcohol misuse.
引用
收藏
页码:1401 / 1425
页数:25
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