Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors

被引：1111
作者：
Gordon, Michael D.
Nusse, Roel [1 ]
机构：
[1] Stanford Univ, Sch Med, Howard Hughes Med Inst, Stanford, CA 94305 USA
[2] Stanford Univ, Sch Med, Dept Dev Biol, Stanford, CA 94305 USA
来源：
JOURNAL OF BIOLOGICAL CHEMISTRY | 2006年 / 281卷 / 32期
关键词：
D O I：
10.1074/jbc.R600015200
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：22429 / 22433
页数：5
相关论文
共 55 条
[1]   Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells [J].
Bänziger, Carla ;
Soldini, Davide ;
Schuett, Corina ;
Zipperlen, Peder ;
Hausmann, George ;
Basler, Konrad .
CELL, 2006, 125 (03) :509-522
[2]   Secretion of Wnt Ligands requires Evi, a conserved transmembrane protein [J].
Bartscherer, Kerstin ;
Pelte, Nadege ;
Ingelfinger, Dierk ;
Boutros, Michael .
CELL, 2006, 125 (03) :523-533
[3]   A new member of the frizzled family from Drosophila functions as a Wingless receptor [J].
Bhanot, P ;
Brink, M ;
Samos, CH ;
Hsieh, JC ;
Wang, YS ;
Macke, JP ;
Andrew, D ;
Nathans, J ;
Nusse, R .
NATURE, 1996, 382 (6588) :225-230
[4]   Cancer genetics: colorectal cancer as a model [J].
Bodmer, WF .
JOURNAL OF HUMAN GENETICS, 2006, 51 (05) :391-396
[5]   Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize β-catenin independently of Frizzled proteins [J].
Brennan, K ;
Gonzalez-Sancho, JM ;
Castelo-Soccio, LA ;
Howe, LR ;
Brown, AMC .
ONCOGENE, 2004, 23 (28) :4873-4884
[6]   pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila [J].
Brunner, E ;
Peter, O ;
Schweizer, L ;
Basler, K .
NATURE, 1997, 385 (6619) :829-833
[7]   Drosophila Tcf and Groucho interact to repress Wingless signalling activity [J].
Cavallo, RA ;
Cox, RT ;
Moline, MM ;
Roose, J ;
Polevoy, GA ;
Clevers, H ;
Peifer, M ;
Bejsovec, A .
NATURE, 1998, 395 (6702) :604-608
[8]   A functional interaction between the histone deacetylase Rpd3 and the corepressor Groucho in Drosophila development [J].
Chen, GQ ;
Fernandez, J ;
Mische, S ;
Courey, AJ .
GENES & DEVELOPMENT, 1999, 13 (17) :2218-2230
[9]   Dishevelled 2 recruits β-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4 [J].
Chen, W ;
ten Berge, D ;
Brown, J ;
Ahn, S ;
Hu, LA ;
Miller, WE ;
Caron, MG ;
Barak, LS ;
Nusse, R ;
Lefkowitz, RJ .
SCIENCE, 2003, 301 (5638) :1391-1394
[10]   Wnt signals across the plasma membrane to activate the β-catenin pathway by forming oligomers containing its receptors, frizzled and LRP [J].
Cong, F ;
Schweizer, L ;
Varmus, H .
DEVELOPMENT, 2004, 131 (20) :5103-5115
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