Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors

被引:1099
作者
Gordon, Michael D.
Nusse, Roel [1 ]
机构
[1] Stanford Univ, Sch Med, Howard Hughes Med Inst, Stanford, CA 94305 USA
[2] Stanford Univ, Sch Med, Dept Dev Biol, Stanford, CA 94305 USA
关键词
D O I
10.1074/jbc.R600015200
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:22429 / 22433
页数:5
相关论文
共 55 条
  • [1] Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells
    Bänziger, Carla
    Soldini, Davide
    Schuett, Corina
    Zipperlen, Peder
    Hausmann, George
    Basler, Konrad
    [J]. CELL, 2006, 125 (03) : 509 - 522
  • [2] Secretion of Wnt Ligands requires Evi, a conserved transmembrane protein
    Bartscherer, Kerstin
    Pelte, Nadege
    Ingelfinger, Dierk
    Boutros, Michael
    [J]. CELL, 2006, 125 (03) : 523 - 533
  • [3] A new member of the frizzled family from Drosophila functions as a Wingless receptor
    Bhanot, P
    Brink, M
    Samos, CH
    Hsieh, JC
    Wang, YS
    Macke, JP
    Andrew, D
    Nathans, J
    Nusse, R
    [J]. NATURE, 1996, 382 (6588) : 225 - 230
  • [4] Cancer genetics: colorectal cancer as a model
    Bodmer, WF
    [J]. JOURNAL OF HUMAN GENETICS, 2006, 51 (05) : 391 - 396
  • [5] Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize β-catenin independently of Frizzled proteins
    Brennan, K
    Gonzalez-Sancho, JM
    Castelo-Soccio, LA
    Howe, LR
    Brown, AMC
    [J]. ONCOGENE, 2004, 23 (28) : 4873 - 4884
  • [6] pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila
    Brunner, E
    Peter, O
    Schweizer, L
    Basler, K
    [J]. NATURE, 1997, 385 (6619) : 829 - 833
  • [7] Drosophila Tcf and Groucho interact to repress Wingless signalling activity
    Cavallo, RA
    Cox, RT
    Moline, MM
    Roose, J
    Polevoy, GA
    Clevers, H
    Peifer, M
    Bejsovec, A
    [J]. NATURE, 1998, 395 (6702) : 604 - 608
  • [8] A functional interaction between the histone deacetylase Rpd3 and the corepressor Groucho in Drosophila development
    Chen, GQ
    Fernandez, J
    Mische, S
    Courey, AJ
    [J]. GENES & DEVELOPMENT, 1999, 13 (17) : 2218 - 2230
  • [9] Dishevelled 2 recruits β-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
    Chen, W
    ten Berge, D
    Brown, J
    Ahn, S
    Hu, LA
    Miller, WE
    Caron, MG
    Barak, LS
    Nusse, R
    Lefkowitz, RJ
    [J]. SCIENCE, 2003, 301 (5638) : 1391 - 1394
  • [10] Wnt signals across the plasma membrane to activate the β-catenin pathway by forming oligomers containing its receptors, frizzled and LRP
    Cong, F
    Schweizer, L
    Varmus, H
    [J]. DEVELOPMENT, 2004, 131 (20): : 5103 - 5115