Pd-catalyzed ligand-free Suzuki reaction of β-substituted allylic halides with arylboronic acids in water

被引：15
作者：
Dong, Chaonan [1 ]
Zhang, Lingjuan [1 ]
Xue, Xiao [1 ]
Li, Huanrong [1 ]
Yu, Zhiyong [1 ]
Tang, Weijun [1 ]
Xu, Lijin [1 ]
机构：
[1] Renmin Univ China, Dept Chem, Beijing 100872, Peoples R China
来源：
RSC ADVANCES | 2014年 / 4卷 / 22期
基金：
中国国家自然科学基金;
关键词：
CROSS-COUPLING REACTIONS; BAYLIS-HILLMAN ADDUCTS; AQUEOUS-MEDIA; ARYL HALIDES; PALLADIUM CATALYSTS; MIYAURA COUPLINGS; BORONIC ACIDS; SUPPORTED PALLADIUM; REUSABLE CATALYST; HIGHLY EFFICIENT;
D O I：
10.1039/c3ra47813k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The catalyst system consisting of Pd(TFA)(2) and KOH allows for a wide range of beta-substituted allylic halides to react efficiently with various arylboronic acids in neat water under ligand-free conditions, affording the allylated arenes in high yields with broad functional group tolerance and up to 7.4 x 10(5) TON and 15 416 h(-1) TOF.
引用
收藏
页码：11152 / 11158
页数：7
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