Total synthesis of nortopsentins A-D, marine alkaloids

被引:0
作者
Kawasaki, I [1 ]
Yamashita, M [1 ]
Ohta, S [1 ]
机构
[1] KYOTO PHARMACEUT UNIV, YAMASHIMA KU, KYOTO 607, JAPAN
关键词
imidazole; marine alkaloid; Suzuki reaction; palladium catalyst; arylboronic acid; nortopsentin;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Nortopsentins A-D, antifungal 1,4-bisindolylimidazole marine alkaloids isolated from a sponge, were synthesized through palladium-catalyzed cross-coupling of 3-indolylboronic and 6-bromo-3-indolylboronic acids with halogenoimidazoles as the key reaction.
引用
收藏
页码:1831 / 1839
页数:9
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