Application of genetic programming coupling with genetic algorithm

被引：0

作者：

Zhou, XD ^{[1
]}

Li, TH ^{[1
]}

Bian, F ^{[1
]}

Quian, JL ^{[1
]}

机构：

[1] Tongji Univ, Dept Chem, Shanghai 200092, Peoples R China

来源：

CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 2000年 / 21卷 / 02期

关键词：

genetic algorithm; genetic programming; QSAR;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

GA-GP is an algorithm for dealing with all kinds of nonlinear function relationships and fraction relationships, which use GP(Genetic programming) to create new individuals and GA(Genetic algorithm) to optimize them at the same time. In this way we make full advantage of GA and GP. We discuss the application of this algorithm in quantitative structure-activity relationship (QSAR) in the medicinal field. The result shows that GA-GP is better than ANN and mathematical expressions could be obtained. Expressions clearly express and explain QSAR of the medicine. All can show GA-GP has very wide applications in the medicinal field of the molecule design.

引用

页码：216 / 218

页数：3