Fetal magnetic resonance imaging in midline malformations of the central nervous system and review of the literature

被引：20
作者：
Dill, P. [1 ]
Poretti, A. [2 ]
Boltshauser, E. [2 ]
Huisman, T. A. G. M. [1 ]
机构：
[1] Johns Hopkins Univ Hosp, Dept Radiol & Radiol Sci, Div Pediat Radiol, Baltimore, MD 21287 USA
[2] Univ Childrens Hosp Zurich, Dept Pediat Neurol, CH-8032 Zurich, Switzerland
来源：
JOURNAL OF NEURORADIOLOGY | 2009年 / 36卷 / 03期
关键词：
Fetal magnetic resonance imaging; Cerebral midline malformation; Holoprosencephaly; Rhombencephalosynapsis; Gomez-Lopez-Hernandez Syndrome; LOPEZ-HERNANDEZ-SYNDROME; SONIC-HEDGEHOG GENE; PRENATAL-DIAGNOSIS; CLINICAL FINDINGS; FACIAL ANOMALIES; RHOMBENCEPHALOSYNAPSIS; BRAIN; MUTATIONS; SPECIFICATION; EPIDEMIOLOGY;
D O I：
10.1016/j.neurad.2008.12.001
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Fetal magnetic resonance imaging (MRI) is a well-established second line imaging modatity in identifying complex pathologies of the central nervous system (CNS), especially when ultrasound (US) findings are equivocal. It may enable an early and precise diagnosis, which is essential in terms of management of pregnancy and pre-, peri- and postnatal care. We present three cases with rare complex midline malformations of the CNS, diagnosed prenatally by fetal MRI. Two cases revealed hotoprosencephaly; one case demonstrated rhombencephalosynapsis. In addition, we reviewed the literature and provide a summary of recent findings regarding cerebral. midline development and discuss the advantages of fetal MRI. (C) 2008 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：138 / 146
页数：9
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