Are DEAD-box proteins becoming respectable helicases?

被引：40

作者：

Linder, P

Daugeron, MC

机构：

[1] Dept Biochim Med CMU, CH-1211 Geneva 4, Switzerland

[2] Univ Paris Sud, Inst Genet & Microbiol, F-91405 Orsay, France

来源：

NATURE STRUCTURAL BIOLOGY | 2000年 / 7卷 / 02期

关键词：

D O I：

10.1038/72464

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The vaccinia NPH-II RNA helicase, a member of the DEAD/DExH-box protein family, has been shown to be a processive, unidirectional RNA helicase with a step size of about one half turn of a helix. This finding demonstrates that RNA helicases can function as molecular motors.

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页码：97 / 99

页数：3

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