Are DEAD-box proteins becoming respectable helicases?

被引:40
作者
Linder, P
Daugeron, MC
机构
[1] Dept Biochim Med CMU, CH-1211 Geneva 4, Switzerland
[2] Univ Paris Sud, Inst Genet & Microbiol, F-91405 Orsay, France
关键词
D O I
10.1038/72464
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The vaccinia NPH-II RNA helicase, a member of the DEAD/DExH-box protein family, has been shown to be a processive, unidirectional RNA helicase with a step size of about one half turn of a helix. This finding demonstrates that RNA helicases can function as molecular motors.
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页码:97 / 99
页数:3
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