The EcoCyc database: reflecting new knowledge about Escherichia coli K-12

被引:389
作者
Keseler, Ingrid M. [1 ]
Mackie, Amanda [2 ]
Santos-Zavaleta, Alberto [3 ]
Billington, Richard [1 ]
Bonavides-Martinez, Cesar [3 ]
Caspi, Ron [1 ]
Fulcher, Carol [1 ]
Gama-Castro, Socorro [3 ]
Kothari, Anamika [1 ]
Krummenacker, Markus [1 ]
Latendresse, Mario [1 ]
Muniz-Rascado, Luis
Ong, Quang [1 ]
Paley, Suzanne [1 ]
Peralta-Gil, Martin [3 ]
Subhraveti, Pallavi [1 ]
Velazquez-Ramirez, David A. [3 ]
Weaver, Daniel [1 ]
Collado-Vides, Julio [3 ]
Paulsen, Ian [2 ]
Karp, Peter D. [1 ]
机构
[1] SRI Int, 333 Ravenswood Ave, Menlo Pk, CA 94025 USA
[2] Macquarie Univ, Dept Chem & Biomol Sci, Sydney, NSW 2109, Australia
[3] Univ Nacl Autonoma Mexico, Ctr Ciencias Genomicas, Programa Genom Computac, Morelos 62100, Mexico
基金
美国国家卫生研究院;
关键词
TRANSCRIPTION FACTOR; SULFUR CYCLE; TRANSPORTER; REGULATOR; GENE; CYSTINE; PROTEIN; SUSCEPTIBILITY; IDENTIFICATION; BIOSYNTHESIS;
D O I
10.1093/nar/gkw1003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
EcoCyc (EcoCyc.org) is a freely accessible, comprehensive database that collects and summarizes experimental data for Escherichia coli K-12, the beststudied bacterial model organism. New experimental discoveries about gene products, their function and regulation, new metabolic pathways, enzymes and cofactors are regularly added to EcoCyc. New SmartTable tools allow users to browse collections of related EcoCyc content. SmartTables can also serve as repositories for user-or curator-generated lists. EcoCyc now supports running and modifying E. coli metabolic models directly on the EcoCyc website.
引用
收藏
页码:D543 / D550
页数:8
相关论文
共 44 条
[1]   Biosynthesis and function of the sulfolipid sulfoquinovosyl diacylglycerol [J].
Benning, C .
ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY, 1998, 49 :53-75
[2]   Questions remaining in sulfolipid biosynthesis: a historical perspective [J].
Benning, Christoph .
PHOTOSYNTHESIS RESEARCH, 2007, 92 (02) :199-203
[3]   The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases [J].
Caspi, Ron ;
Billington, Richard ;
Ferrer, Luciana ;
Foerster, Hartmut ;
Fulcher, Carol A. ;
Keseler, Ingrid M. ;
Kothari, Anamika ;
Krummenacker, Markus ;
Latendresse, Mario ;
Mueller, Lukas A. ;
Ong, Quang ;
Paley, Suzanne ;
Subhraveti, Pallavi ;
Weaver, Daniel S. ;
Karp, Peter D. .
NUCLEIC ACIDS RESEARCH, 2016, 44 (D1) :D471-D480
[4]   Sulphoglycolysis in Escherichia coli K-12 closes a gap in the biogeochemical sulphur cycle [J].
Denger, Karin ;
Weiss, Michael ;
Felux, Ann-Katrin ;
Schneider, Alexander ;
Mayer, Christoph ;
Spiteller, Dieter ;
Huhn, Thomas ;
Cook, Alasdair M. ;
Schleheck, David .
NATURE, 2014, 507 (7490) :114-+
[5]   Sulfoquinovose degraded by pure cultures of bacteria with release of C3-organosulfonates: complete degradation in two-member communities [J].
Denger, Karin ;
Huhn, Thomas ;
Hollemeyer, Klaus ;
Schleheck, David ;
Cook, Alasdair M. .
FEMS MICROBIOLOGY LETTERS, 2012, 328 (01) :39-45
[6]   Susceptibility of Escherichia coli to the toxic L-proline analogue L-selenaproline is dependent on two L-cystine transport systems [J].
Deutch, C. E. ;
Spahija, I. ;
Wagner, C. E. .
JOURNAL OF APPLIED MICROBIOLOGY, 2014, 117 (05) :1487-1499
[7]   The Highly Conserved MraZ Protein Is a Transcriptional Regulator in Escherichia coli [J].
Eraso, Jesus M. ;
Markillie, Lye M. ;
Mitchell, Hugh D. ;
Taylor, Ronald C. ;
Orr, Galya ;
Margolin, William .
JOURNAL OF BACTERIOLOGY, 2014, 196 (11) :2053-2066
[8]   Newly Identified Genetic Variations in Common Escherichia coli MG1655 Stock Cultures [J].
Freddolino, Peter L. ;
Amini, Sasan ;
Tavazoie, Saeed .
JOURNAL OF BACTERIOLOGY, 2012, 194 (02) :303-306
[9]   Identification of a Target Gene and Activating Stimulus for the YpdA/YpdB Histidine Kinase/Response Regulator System in Escherichia coli [J].
Fried, Luitpold ;
Behr, Stefan ;
Jung, Kirsten .
JOURNAL OF BACTERIOLOGY, 2013, 195 (04) :807-815
[10]   Repairing oxidized proteins in the bacterial envelope using respiratory chain electrons [J].
Gennaris, Alexandra ;
Ezraty, Benjamin ;
Henry, Camille ;
Agrebi, Rym ;
Vergnes, Alexandra ;
Oheix, Emmanuel ;
Bos, Julia ;
Leverrier, Pauline ;
Espinosa, Leon ;
Szewczyk, Joanna ;
Vertommen, Didier ;
Iranzo, Olga ;
Collet, Jean-Francois ;
Barras, Frederic .
NATURE, 2015, 528 (7582) :409-+