Epidemiology of aortic aneurysm repair in the United States from 2000 to 2010

被引:383
作者
Dua, Anahita [1 ,2 ]
Kuy, SreyRam [2 ]
Lee, Cheong J. [2 ]
Upchurch, Gilbert R., Jr. [3 ]
Desai, Sapan S. [4 ]
机构
[1] Univ Texas Houston, Dept Surg, Ctr Translat Injury Res CeTIR, Houston, TX USA
[2] Med Coll Wisconsin, Dept Surg, Div Vasc Surg, Milwaukee, WI 53226 USA
[3] Univ Virginia, Dept Surg, Charlottesville, VA USA
[4] Duke Univ, Dept Surg, Durham, NC 27710 USA
关键词
ENDOVASCULAR REPAIR; RANDOMIZED-TRIALS; METAANALYSIS; OUTCOMES; GENDER; IMPACT; WOMEN;
D O I
10.1016/j.jvs.2014.01.007
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objective: Broad application of endovascular aneurysm repair (EVAR) has led to a rapid decline in open aneurysm repair (OAR) and improved patient survival, albeit at a higher overall cost of care. The aim of this report is to evaluate national trends in the incidence of unruptured and ruptured abdominal aortic aneurysms (AAAs), their management by EVAR and OAR, and to compare overall patient characteristics and clinical outcomes between these two approaches. Methods: A retrospective analysis of the cross-sectional National Inpatient Sample (2000-2010) was used to evaluate patient characteristics and outcomes related to EVAR and OAR for unruptured and ruptured AAAs. Data were extrapolated to represent population-level statistics through the use of data from the U. S. Census Bureau. Comparisons between groups were made with the use of descriptive statistics. Results: There were 101,978 patients in the National Inpatient Sample affected by AAAs over the 11-year span of this study; the average age was 73 years, 21% were women, and 90% were white. Overall in-hospital mortality rate was 7%, with a median length of stay (LOS) of 5 days and median hospital charges of $58,305. In-hospital mortality rate was 13 times greater for ruptured patients, with a median LOS of 9 days and median charges of $84,744. For both unruptured and ruptured patients, EVAR was associated with a lower in-hospital mortality rate (4% vs 1% for unruptured and 41% vs 27% for ruptured; P < .001 for each), shorter median LOS (7 vs 2; 9 vs 6; P < .001) but a 27%-36% increase in hospital charges. Conclusions: The overall use of EVAR has risen sharply in the past 10 years (5.2% to 74% of the total number of AAA repairs) even though the total number of AAAs remains stable at 45,000 cases per year. In-hospital mortality rates for both ruptured and unruptured cases have fallen by more than 50% during this time period. Lower mortality rates and shorter LOS despite a 27%-36% higher cost of care continues to justify the use of EVAR over OAR. For patients with suitable anatomy, EVAR should be the preferred management of both ruptured and unruptured AAAs.
引用
收藏
页码:1512 / 1517
页数:6
相关论文
共 18 条
[1]  
Barker WF, 1992, CLIO CHIRURG ARTERIE, P273
[2]   A randomized controlled trial of endovascular aneurysm repair versus open surgery for abdominal aortic aneurysms in low- to moderate-risk patients [J].
Becquemin, Jean-Pierre ;
Pillet, Jean-Chistophe ;
Lescalie, Francois ;
Sapoval, Marc ;
Goueffic, Yann ;
Lermusiaux, Patrick ;
Steinmetz, Eric ;
Marzelle, Jean .
JOURNAL OF VASCULAR SURGERY, 2011, 53 (05) :1167-1173
[3]   The UK EndoVascular Aneurysm Repair (EVAR) trials: randomised trials of EVAR versus standard therapy [J].
Brown, L. C. ;
Powell, J. T. ;
Thompson, S. G. ;
Epstein, D. M. ;
Sculpher, M. J. ;
Greenhalgh, R. M. .
HEALTH TECHNOLOGY ASSESSMENT, 2012, 16 (09) :1-+
[4]   The risk of rupture in untreated aneurysms: The impact of size, gender, and expansion rate [J].
Brown, PM ;
Zelt, DT ;
Sobolev, B .
JOURNAL OF VASCULAR SURGERY, 2003, 37 (02) :280-283
[5]   Ten-year results of endovascular abdominal aortic aneurysm repair from a large multicenter registry [J].
Chang, Robert W. ;
Goodney, Philip ;
Tucker, Lue-Yen ;
Okuhn, Steven ;
Hua, Hong ;
Rhoades, Ann ;
Sivamurthy, Nayan ;
Hill, Bradley .
JOURNAL OF VASCULAR SURGERY, 2013, 58 (02) :324-331
[6]   Open Versus Endovascular Stent Graft Repair of Abdominal Aortic Aneurysms A Meta-Analysis of Randomized Trials [J].
Dangas, George ;
O'Connor, David ;
Firwana, Belal ;
Brar, Somjot ;
Ellozy, Sharif ;
Vouyouka, Angeliki ;
Arnold, Margaret ;
Kosmas, Constantine E. ;
Krishnan, Prakash ;
Wiley, Jose ;
Suleman, Javed ;
Olin, Jeffrey ;
Marin, Michael ;
Faries, Peter .
JACC-CARDIOVASCULAR INTERVENTIONS, 2012, 5 (10) :1071-1080
[7]   Long-Term Outcome of Open or Endovascular Repair of Abdominal Aortic Aneurysm [J].
De Bruin, Jorg L. ;
Baas, Annette F. ;
Buth, Jaap ;
Prinssen, Monique ;
Verhoeven, Eric L. G. ;
Cuypers, Philippe W. M. ;
van Sambeek, Marc R. H. M. ;
Balm, Ron ;
Grobbee, Diederick E. ;
Blankensteijn, Jan D. .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (20) :1881-1889
[8]   Gender-specific Influences on the Results of Vascular Surgery [J].
Grundmann, R. T. ;
Meyer, F. .
ZENTRALBLATT FUR CHIRURGIE, 2013, 138 (02) :210-218
[9]   ACC/AHA 2005 guidelines for the management of patients with peripheral arterial disease (Lower extremity, renal, mesenteric, and abdominal aortic): Executive summary [J].
Hirsch, AT ;
Haskal, ZJ ;
Hertzer, NR ;
Bakal, CW ;
Creager, MA ;
Halperin, JL ;
Hiratzka, LF ;
Murphy, WRC ;
Olin, JW ;
Puschett, JB ;
Rosenfield, KA ;
Sacks, D ;
Stanley, JC ;
Taylor, LM ;
White, CJ ;
White, J ;
White, RA ;
Antman, EM ;
Smith, SC ;
Adams, CD ;
Anderson, JL ;
Faxon, DP ;
Fuster, V ;
Gibbons, RJ ;
Halperin, JL ;
Hiratzka, LF ;
Hunt, SA ;
Jacobs, AK ;
Nishimura, R ;
Ornato, JP ;
Page, RL ;
Riegel, B .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 47 (06) :1239-1312
[10]  
JOHNSON G, 1985, ARCH SURG-CHICAGO, V120, P1138