Key questions about the future of laboratory medicine in the next decade of the 21st century: A report from the IFCC-Emerging Technologies Division

被引:45
作者
Greaves, Ronda F. [1 ,2 ]
Bernardini, Sergio [3 ]
Ferraris, Maurizio [4 ,5 ]
Fortina, Paolo [6 ]
Gouget, Bernard [7 ]
Gruson, Damien [8 ]
Lang, Tim [9 ]
Loh, Tze Ping [10 ,11 ]
Morris, Howard A. [12 ]
Park, Jason Y. [13 ,14 ,15 ]
Roessler, Markus [16 ]
Yin, Peng [17 ]
Kricka, Larry J. [18 ]
机构
[1] Murdoch Childrens Res Inst, Victorian Clin Genet Serv, Parkville, Vic, Australia
[2] RMIT Univ, Sch Hlth & Biomed Sci, Melbourne, Vic, Australia
[3] Univ Tor Vergata, Dept Expt Med, Rome, Italy
[4] Univ Vita Salute San Raffaele, Milan, Italy
[5] IRCCS San Raffaele Hosp, Milan, Italy
[6] Thomas Jefferson Univ, Dept Canc Biol, Kimmel Canc Ctr, Philadelphia, PA 19107 USA
[7] Comm Com Francais Accreditat Cofrac, President Healthcare Div, Paris, France
[8] Clinl Univ St Luc, Dept Lab Clin, Biochim Med, Brussels, Belgium
[9] Univ Hosp North Durham, Durham, England
[10] Sengkang Gen Hosp, Dept Pathol, Singapore, Singapore
[11] Natl Univ Singapore Hosp, Dept Lab Med, Singapore, Singapore
[12] Univ South Australia, Sch Pharm & Med Sci, Adelaide, SA, Australia
[13] Childrens Med Ctr, Dept Pathol, 1935 Med Dist Dr, Dallas, TX 75235 USA
[14] Childrens Med Ctr, Eugene McDermott Ctr Human Growth & Dev, 1935 Med Dist Dr, Dallas, TX 75235 USA
[15] Univ Texas Southwestern Med Sch, 1935 Med Dist Dr, Dallas, TX 75235 USA
[16] Roche Diagnost GmbH, Centralised & Point Of Care Solut Early Dev & Rea, Penzberg, Germany
[17] Abbott Diagnost Div, Shanghai, Peoples R China
[18] Univ Penn, Med Ctr, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
关键词
Emerging technologies; Disruptive technologies; Laboratory medicine; ELECTRONIC HEALTH RECORDS; TANDEM MASS-SPECTROMETRY; QUALITY-ASSURANCE; LIBERTARIAN RIGHT; VALUE PROPOSITION; INBORN-ERRORS; MOVING SUM; OF-CARE; MANAGEMENT; BLOOD;
D O I
10.1016/j.cca.2019.05.021
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
This review advances the discussion about the future of laboratory medicine in the 2020s. In five major topic areas: 1. the "big picture" of healthcare; 2. pre-analytical factors; 3. Analytical factors; 4. post-analytical factors; and 5. relationships, which explores a next decade perspective on laboratory medicine and the likely impact of the predicted changes by means of a number of carefully focused questions that draw upon predictions made since 2013. The "big picture" of healthcare explores the effects of changing patient populations, the brain-to-brain loop, direct access testing, robots and total laboratory automation, and green technologies and sustain ability. The pre-analytical section considers the role of different sample types, drones, and biobanks. The analytical section examines advances in point-of-care testing, mass spectrometry, genomics, gene and immunotherapy, 3D-printing, and total laboratory quality. The post-analytical section discusses the value of laboratory medicine, the emerging role of artificial intelligence, the management and interpretation of omics data, and common reference intervals and decision limits. Finally, the relationships section explores the role of laboratory medicine scientific societies, the educational needs of laboratory professionals, communication, the relationship between laboratory professionals and clinicians, laboratory medicine financing, and the anticipated economic opportunities and outcomes in the 2020's.
引用
收藏
页码:570 / 589
页数:20
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