A Case of IgG4-Related Disease with Bronchial Asthma and Chronic Rhinosinusitis in Korea

被引:14
作者
Lee, Young-Soo [1 ]
Cho, Hyo-Jeong [1 ]
Yoo, Hye-Soo [1 ]
Shin, Yoo-Sub [1 ]
Park, Hae-Sim [1 ]
机构
[1] Ajou Univ, Sch Med, Dept Allergy & Clin Immunol, Suwon 443721, South Korea
关键词
IgG4-Related Disease; Asthma; Bronchitis; Chronic; AUTOIMMUNE PANCREATITIS; SCLEROSING PANCREATITIS; TH2; MANIFESTATIONS; CELLS;
D O I
10.3346/jkms.2014.29.4.599
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
IgG4-related disease (IgG4-RD) is characterized by a systemic involvement of tumor-like lesions with IgG4-positive plasmacytes. We experienced a case of IgG4-RD developed in a patient with bronchial asthma (BA) and chronic rhinosinusitis (CRS). A 55-yr-old female patient with BA and CRS complained of both eyes and neck swelling as well as a recurrent upper respiratory infection in recent 1 yr. The serum levels of IgG4, creatinine, and pancreatic enzymes were elevated. A biopsy of the submandibular gland showed an abundant infiltration of IgG4-positive plasmacytes. Her symptoms remarkably improved after the treatment of a systemic steroid that has been maintained without recurrence. We report a rare case of IgG4-RD developed in a patient with BA and CRS.
引用
收藏
页码:599 / 603
页数:5
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