Apatite formation on non-woven fabric of carboxymethylated chitin in SBF

被引：66

作者：

Kokubo, T

Hanakawa, M

Kawashita, M ^{[1
]}

Minoda, M

Beppu, T

Miyamoto, T

Nakamura, T

机构：

[1] Kyoto Univ, Dept Chem Mat, Grad Sch Engn, Nishikyo Ku, Kyoto 6158501, Japan

[2] Chubu Univ, Res Inst Sci & Technol, Kasugai, Aichi 4878501, Japan

[3] Kyoto Inst Technol, Dept Chem & Mat Technol, Fac Engn & Design, Kyoto 6068585, Japan

[4] Matsue Natl Coll Technol, Matsue, Shimane 6908518, Japan

[5] Kyoto Univ, Dept Orthopaed Surg, Grad Sch Med, Sakyo Ku, Kyoto 6068507, Japan

来源：

BIOMATERIALS | 2004年 / 25卷 / 18期

基金：

日本学术振兴会;

关键词：

apatite; carboxymethylated chitin; non-woven fabric; carboxyl groups; biomimetic process; simulated body fluid;

D O I：

10.1016/j.biomaterials.2003.11.007

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Chitin fibres constituting a non-woven fabric were carboxymethylated in monochloro acetic acid and treated with saturated Ca(OH)(2) aqueous solution. Within 3 days in a simulated body fluid with pH value and ion concentrations nearly equal to those of human blood plasma, a bonelike apatite layer formed on the surface of fibres of the treated fabric. The apatite-chitin fibre composite thus prepared is expected to be useful as a flexible bioactive bone-repairing material. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：4485 / 4488

页数：4

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