Apatite formation on non-woven fabric of carboxymethylated chitin in SBF

被引：65
|
作者：
Kokubo, T
Hanakawa, M
Kawashita, M [1 ]
Minoda, M
Beppu, T
Miyamoto, T
Nakamura, T
机构：
[1] Kyoto Univ, Dept Chem Mat, Grad Sch Engn, Nishikyo Ku, Kyoto 6158501, Japan
[2] Chubu Univ, Res Inst Sci & Technol, Kasugai, Aichi 4878501, Japan
[3] Kyoto Inst Technol, Dept Chem & Mat Technol, Fac Engn & Design, Kyoto 6068585, Japan
[4] Matsue Natl Coll Technol, Matsue, Shimane 6908518, Japan
[5] Kyoto Univ, Dept Orthopaed Surg, Grad Sch Med, Sakyo Ku, Kyoto 6068507, Japan
来源：
BIOMATERIALS | 2004年 / 25卷 / 18期
基金：
日本学术振兴会;
关键词：
apatite; carboxymethylated chitin; non-woven fabric; carboxyl groups; biomimetic process; simulated body fluid;
D O I：
10.1016/j.biomaterials.2003.11.007
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Chitin fibres constituting a non-woven fabric were carboxymethylated in monochloro acetic acid and treated with saturated Ca(OH)(2) aqueous solution. Within 3 days in a simulated body fluid with pH value and ion concentrations nearly equal to those of human blood plasma, a bonelike apatite layer formed on the surface of fibres of the treated fabric. The apatite-chitin fibre composite thus prepared is expected to be useful as a flexible bioactive bone-repairing material. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4485 / 4488
页数：4
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