Recent Advances in Application of Amino Acids: Key Building Blocks in Design and Syntheses of Heterocyclic Compounds

被引：74

作者：

Heravi, Majid M. ^{[1
]}

Vavsari, Vaezeh Fathi ^{[1
]}

机构：

[1] Alzahra Univ, Sch Sci, Dept Chem, Tehran, Iran

来源：

ADVANCES IN HETEROCYCLIC CHEMISTRY, VOL 114 | 2015年 / 114卷

关键词：

Amino acids; Asymmetric synthesis; Bifunctional; Chiral catalyst; Heterocyclization; Natural products; SOLID-PHASE SYNTHESIS; ENANTIOSELECTIVE TOTAL-SYNTHESIS; COMBINATORIAL ORGANIC-SYNTHESIS; PICTET-SPENGLER REACTION; INTRAMOLECULAR ENYNE METATHESIS; 1,3-DIPOLAR CYCLOADDITION; ASYMMETRIC-SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; FLUOROUS SYNTHESIS; PEPTIDE-SYNTHESIS;

D O I：

10.1016/bs.aihch.2015.02.002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Amino acids (AAs) are usually considered as important scaffolds for peptides and proteins. However, in the past decades, they have been extensively used as important synthons for the syntheses of a variety of heterocyclic systems, especially for those in which one particular stereoisomer should be obtained via asymmetric synthesis. Although the applications of AAs as synthons in heterocyclization were extensively reviewed in 1995, numerous recent reports concerning their use for the construction of a wide variety of differently sized heterocycles make the subject worthwhile of update.

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页码：77 / 145

页数：69

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