A gold-catalyzed facile intramolecular rearrangement and cyclization sequence for synthesis of 2,5-dihydrofurans

被引：14
|
作者：
Sunil, Komalla [1 ]
Thummala, Yadagiri [1 ,2 ]
Dalovai, Purnachandar [1 ,2 ]
Balasubramanian, Sridhar [3 ]
Karunakar, Galla V. [1 ,2 ]
机构：
[1] Indian Inst Chem Technol, CSIR, Dept Fluoro & Agrochem, Hyderabad 500007, Andhra Pradesh, India
[2] Acad Sci & Innovat Res, Ghaziabad 201002, India
[3] Indian Inst Chem Technol, CSIR, Ctr Xray Crystallog, Hyderabad 500007, Andhra Pradesh, India
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2019年 / 17卷 / 24期
关键词：
PROPARGYLIC BETA-ENAMINONES; IN-VITRO; ANTIMICROBIAL ACTIVITY; CYTOTOXIC ACTIVITY; GONIOTHALAMIN; DERIVATIVES; ACIDS; GONIOBUTENOLIDES; DIHYDROFURANS; ALCOHOLS;
D O I：
10.1039/c9ob00756c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient gold-catalyzed intramolecular rearrangement and cyclization protocol was developed for synthesis of 2,5-dihydrofuran derivatives from O-propargyl beta-enaminones. In this organic transformation new C-C and C-O bonds are formed under mild reaction conditions; this includes the formation of a quaternary centre.
引用
收藏
页码：6015 / 6024
页数：10
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