The role of adrenaline in cardiopulmonary resuscitation

被引:81
作者
Gough, Christopher J. R. [1 ]
Nolan, Jerry P. [1 ,2 ]
机构
[1] Royal United Hosp, Anaesthesia & Intens Care Med, Bath BA1 3NG, Avon, England
[2] Univ Bristol, Bristol Med Sch, Resuscitat Med, Bristol, Avon, England
来源
CRITICAL CARE | 2018年 / 22卷
关键词
Cardiac arrest; Cardiopulmonary resuscitation; Adrenaline; Epinephrine; Outcome; HOSPITAL CARDIAC-ARREST; PREHOSPITAL EPINEPHRINE; SPONTANEOUS CIRCULATION; BLOOD-FLOW; OUTCOMES; SURVIVAL; TRIAL; PORCINE; VASOPRESSIN; PERFUSION;
D O I
10.1186/s13054-018-2058-1
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Adrenaline has been used in the treatment of cardiac arrest for many years. It increases the likelihood of return of spontaneous circulation (ROSC), but some studies have shown that it impairs cerebral microcirculatory flow. It is possible that better short-term survival comes at the cost of worse long-term outcomes. This narrative review summarises the rationale for using adrenaline, significant studies to date, and ongoing research.
引用
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页数:8
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