Hypermetabolism During Resting-State FDG-PET Suggesting Intrinsic Epileptogenicity in Focal Cortical Dysplasia

被引：0

作者：

Namer, Izzie Jacques ^{[1
,2
]}

Valenti-Hirsch, Maria Paola

Scholly, Julia

Lannes, Beatrice ^{[3
]}

Imperiale, Alessio ^{[1
]}

Hirsch, Edouard

机构：

[1] Univ Strasbourg, CNRS, ICube, Strasbourg, France

[2] Federat Med Translat Strasbourg, Fac Med, Strasbourg, France

[3] Hop Univ Strasbourg, Hop Hautepierre, Serv Anat Pathol, F-67098 Strasbourg 09, France

来源：

CLINICAL NUCLEAR MEDICINE | 2014年 / 39卷 / 11期

关键词：

Epilepsy; Focal cortical dysplasia; FDG; PET; EEG; stereo-EEG; MRI; EPILEPSY; CLASSIFICATION; SURGERY;

D O I：

暂无

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We report the case of a 21-year-old man who presented drug-resistant epilepsy since the age of 3 years. The underlying type Ia left prefrontal focal cortical dysplasia was revealed by focal hypermetabolism of FDG-PET several years later. The stereo-electroencephalography showed continuous interictal rhythmic spike discharges, suggesting the dysplastic character of the cortex explored by depth electrodes placed into and at the margins of PET abnormalities. The surgical limits of resection were defined based on interictal activity, spontaneous and induced seizures. The patient is seizure-free, with normal electroencephalography and clear improvement of neuropsychological performance, without functional deficit at 3 years postsurgery.

引用

页码：993 / 995

页数：3

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