Systemic Inflammation Complicates the Interpretation of Therapeutic Drug Monitoring of Risperidone

被引:7
作者
Helland, Arne [1 ,2 ]
Habib, Simone [3 ]
Ulvestad, Line [3 ]
Spigset, Olav [1 ,2 ]
机构
[1] Norwegian Univ Sci & Technol, Dept Clin Pharmacol, St Olav Univ Hosp, Trondheim, Norway
[2] Norwegian Univ Sci & Technol, Dept Clin & Mol Med, Trondheim, Norway
[3] More & Romsdal Hosp Trust, Dept Psychiat, More And Romsdal, Norway
关键词
SERUM CONCENTRATIONS; METABOLISM; ABSORPTION; CLOZAPINE; EXCRETION; PROTEIN; ENZYMES; BINDING; HUMANS;
D O I
10.1097/JCP.0000000000000873
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:263 / 265
页数:3
相关论文
共 14 条
[1]   Regulation of drug-metabolizing enzymes and transporters in inflammation [J].
Aitken, AE ;
Richardson, TA ;
Morgan, ET .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2006, 46 :123-149
[2]   Effects of age and gender on the serum levels of clozapine, olanzapine, risperidone, and quetiapine [J].
Castberg, I. ;
Westin, A. A. ;
Skogvoll, E. ;
Spigset, O. .
ACTA PSYCHIATRICA SCANDINAVICA, 2017, 136 (05) :455-464
[3]   Immunological response as a source to variability in drug metabolism and transport [J].
Christensen, Hege ;
Hermann, Monica .
FRONTIERS IN PHARMACOLOGY, 2012, 3
[4]   A Puzzling Case of Increased Serum Clozapine Levels in a Patient With Inflammation and Infection [J].
Espnes, Ketil Arne ;
Heimdal, Kent Ove ;
Spigset, Olav .
THERAPEUTIC DRUG MONITORING, 2012, 34 (05) :489-492
[5]   Inflammation and psychotropic drugs: the relationship between C-reactive protein and antipsychotic drug levels [J].
Hefner, Gudrun ;
Shams, Mohamed E. E. ;
Unterecker, Stefan ;
Falter, Tanja ;
Hiemke, Christoph .
PSYCHOPHARMACOLOGY, 2016, 233 (09) :1695-1705
[6]   Elevated risperidone serum concentrations during acute inflammation, two cases [J].
Hefner, Gudrun ;
Falter, Tanja ;
Bruns, Kai ;
Hiemke, Christoph .
INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE, 2015, 50 (03) :335-344
[7]  
Hiemke C, 2011, PHARMACOPSYCHIATRY, V44, P195, DOI 10.1055/s-0031-1286287
[8]  
Huang ZQ, 2013, CURR DRUG METAB, V14, P226
[9]  
MANNENS G, 1993, DRUG METAB DISPOS, V21, P1134
[10]   PLASMA-PROTEIN BINDING OF RISPERIDONE AND ITS DISTRIBUTION IN BLOOD [J].
MANNENS, G ;
MEULDERMANS, W ;
SNOECK, E ;
HEYKANTS, J .
PSYCHOPHARMACOLOGY, 1994, 114 (04) :566-572