Clinical outcomes of patients with Klebsiella pneumoniae carbapenemase-producing K. pneumoniae after treatment with imipenem or meropenem

被引：93
作者：
Weisenberg, Scott A. [1 ]
Morgan, Daniel J. [3 ]
Espinal-Witter, Rosanny [2 ]
Larone, Davise H. [2 ]
机构：
[1] Cornell Univ, Dept Med, Weill Med Coll, New York, NY 10065 USA
[2] Cornell Univ, Dept Pathol, Weill Med Coll, New York, NY 10065 USA
[3] Univ Maryland, Dept Epidemiol & Prevent Med, Baltimore, MD 21201 USA
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2009年 / 64卷 / 02期
关键词：
KPC; Klebsiella pneumoniae; NEW-YORK-CITY; BETA-LACTAMASE; EMERGENCE; SPREAD;
D O I：
10.1016/j.diagmicrobio.2009.02.004
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae may appear susceptible to imipenem or meropenem by routine susceptibility testing. We report a series of patients with infection, caused by K. pneumoniae isolates, which yield imipenem-susceptible results but were subsequently KPC-positive by polymerase chain reaction. When these infections were treated with imipenem or meropenem. frequent clinical and microbiologic failures were observed. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码：233 / 235
页数：3
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