Electronic Detection Of Bacteria Using Holey Reduced Graphene Oxide

被引:46
作者
Chen, Yanan [1 ]
Michael, Zachary P. [1 ]
Kotchey, Gregg P. [1 ]
Zhao, Yong [1 ]
Star, Alexander [1 ]
机构
[1] Univ Pittsburgh, Pittsburgh, PA 15260 USA
基金
美国国家科学基金会;
关键词
graphene; antimicrobial peptides; semiconductors; nanotechnology; nanomaterials; WALLED CARBON NANOTUBES; ANTIMICROBIAL PEPTIDES; IMMEDIATE DETECTION; ESCHERICHIA-COLI; BIOSENSOR; ACID;
D O I
10.1021/am500364f
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Carbon nanomaterials have been widely explored for diverse biosensing applications including bacterial detection. However, covalent functionalization of these materials can lead to the destruction of attractive electronic properties. To this end, we utilized a new graphene derivative holey reduced graphene oxide (hRGO), functionalized with Magainin I to produce a broad-spectrum bacterial probe. Unlike related carbon nanomaterials, hRGO retains the necessary electronic properties while providing the high percentage of available oxygen moieties required for effective covalent functionalization.
引用
收藏
页码:3805 / 3810
页数:6
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