Lactic acidosis induced by metformin in a chronic hemodialysis patient with diabetes mellitus type 2

被引：6

作者：

Altun, Eda ^{[1
]}

Kaya, Bulent ^{[1
]}

Paydas, Saime ^{[1
]}

Sariakcali, Baris ^{[2
]}

Karayaylali, Ibrahim ^{[1
]}

机构：

[1] Cukurova Univ, Dept Nephrol, Fac Med, TR-01130 Adana, Turkey

[2] Cukurova Univ, Dept Endocrinol, Fac Med, TR-01130 Adana, Turkey

来源：

HEMODIALYSIS INTERNATIONAL | 2014年 / 18卷 / 02期

关键词：

Hemodialysis; lactic acidosis; metformin; type 2 diabetes mellitus; ANTIDIABETIC MEDICATIONS;

D O I：

10.1111/hdi.12109

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Metformin is a biguanide group oral antidiabetic drug used for the treatment of type 2 diabetes mellitus. Nausea, vomiting, diarrhea, abdominal pain, and anorexia are the most common adverse effects encountered during treatment. Lactic acidosis is a serious side effect seen with metformin use, and while the incidence of lactic acidosis is similar to other oral antidiabetics, metformin is not recommended to patients with certain risk factors, such as cardiovascular, pulmonary, and renal and liver failure. We describe a chronic hemodialysis patient treated with metformin, presenting to the nephrology department with altered mental status.

引用

页码：529 / 531

页数：3

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