Health and wealth in children and adolescents with chronic kidney disease (K-CAD study)

被引:20
作者
Wong, Germaine [1 ,2 ,3 ]
Medway, Meredith [1 ]
Didsbury, Madeleine [1 ]
Tong, Allison [2 ]
Turner, Robin [4 ]
Mackie, Fiona [5 ]
McTaggart, Steven [6 ]
Walker, Amanda [7 ]
White, Sarah [8 ]
Howard, Kirsten [2 ]
Kim, Siah [1 ]
Craig, Jonathan C. [2 ]
机构
[1] Childrens Hosp Westmead, Kids Res Inst, Ctr Kidney Res, Sydney, NSW, Australia
[2] Univ Sydney, Sydney Sch Publ Hlth, Sydney, NSW 2006, Australia
[3] Westmead Hosp, Ctr Transplant & Renal Res, Sydney, NSW, Australia
[4] Univ New S Wales, Dept Biostat, Sydney, NSW, Australia
[5] Sydney Childrens Hosp Randwick, Dept Renal Med, Sydney, NSW, Australia
[6] Royal Childrens Hosp, Dept Renal Med, Brisbane, Qld, Australia
[7] Royal Childrens Hosp, Dept Renal Med, Melbourne, Vic, Australia
[8] Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia
关键词
Socioeconomic status; Chronic kidney disease; Quality of life; Mortality; Cohort studies; Qualitative; YOUNG-ADULTS; SURVIVAL;
D O I
10.1186/1471-2458-14-307
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background: The impact of reduced kidney function in children is substantial. End-stage kidney disease (ESKD), the most severe form of chronic kidney disease (CKD), is a devastating illness associated with substantially increased mortality, impaired growth and psychosocial maladjustment in children. Understanding how to address the complex causes of mortality and morbidity in children with CKD requires explicit information about the risk factors that lead to adverse outcomes. In addition to biological influences, the socioeconomic circumstances of caregivers may play a significant role in the health and well-being of children with CKD. Methods/Design: A prospective cohort study (n = 380 children and n = 380 caregivers) will be conducted to determine the prevalence of economic hardship among caregivers of children with CKD. All participants will be followed biennially over a period of 5 years to determine the association between the changing socioeconomic status of the caregivers and the health and overall well-being of school-aged children with CKD. Face to face, semi-structured interviews with the caregivers (n = 45) will also be conducted to understand their perspectives on the economic, financial and psychosocial impact of CKD and how this affects the health outcomes of their child with CKD. The primary outcomes of the study are the effects of the socioeconomic status of the caregivers and self-reported health status of the children. Secondary outcomes included the prevalence of economic hardship and the distribution of wealth among the caregivers of children with CKD. Discussion: Findings from this study presents not only a snapshot of the current economic and social situation of the caregivers of children and adolescents with CKD but will also provide definitive evidence of determining whether a link between socioeconomic status of caregivers and outcomes of children with CKD exists.
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页数:5
相关论文
共 12 条
[1]   Socioeconomic status and chronic kidney disease at presentation to a renal service in the United Kingdom [J].
Bello, Aminu K. ;
Peters, Jean ;
Rigby, Jan ;
Rahman, Alhussein A. ;
El Nahas, Meguid .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2008, 3 (05) :1316-1323
[2]   Sociodemographics, self-rated health, and mortality in the US [J].
Franks, P ;
Gold, MR ;
Fiscella, K .
SOCIAL SCIENCE & MEDICINE, 2003, 56 (12) :2505-2514
[3]  
Jaramillo-Solorio RM, 1996, PERITON DIALYSIS INT, V16, P554
[4]   Characteristics and survival of young adults who started renal replacement therapy during childhood [J].
Kramer, Anneke ;
Stel, Vianda S. ;
Tizard, Jane ;
Verrina, Enrico ;
Ronnholm, Kai ;
Palsson, Runolfur ;
Maxwell, Heather ;
Jager, Kitty J. .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2009, 24 (03) :926-933
[5]   The economic burden of asthma in US children: Estimates from the National Medical Expenditure Survey [J].
Lozano, P ;
Sullivan, SD ;
Smith, DH ;
Weiss, KB .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1999, 104 (05) :957-963
[6]   Behavioral disorders and low quality of life in children and adolescents with chronic kidney disease [J].
Marciano, Renata C. ;
Bouissou Soares, Cristina M. ;
Diniz, Jose Silverio S. ;
Lima, Eleonora M. ;
Silva, Jose Maria P. ;
Canhestro, Monica R. ;
Gazzinelli, Andrea ;
Melo, Carla Cristina D. ;
Dias, Cristiane S. ;
Simoes e Silva, Ana Cristina ;
Correa, Humberto ;
Oliveira, Eduardo A. .
PEDIATRIC NEPHROLOGY, 2011, 26 (02) :281-290
[7]   Long-term survival of children with end-stage renal disease [J].
McDonald, SP ;
Craig, JC .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (26) :2654-2662
[8]  
Roberge R, 1929, HLTH REP, V7, P25
[9]   Quality of Life of Young Adults and Adolescents with Chronic Kidney Disease [J].
Tong, Allison ;
Wong, Germaine ;
McTaggart, Steve ;
Henning, Paul ;
Mackie, Fiona ;
Carroll, Robert P. ;
Howard, Kirsten ;
Craig, Jonathan C. .
JOURNAL OF PEDIATRICS, 2013, 163 (04) :1179-+
[10]  
Turrell G., 2006, Health Inequalities in Australia: morbidity, health behaviours, risk factors and health service use