Assessment of the human risk by an intake of ethyl carbamate present in major Korean fermented foods

被引:0
作者
Noh, I-Woo
Ha, Mi-Sun
Han, Eun-Mee
Jang, In-Sook
An, Youn-Joo
Ha, Sang-Do
Park, Sang Kyu
Bae, Dong-Ho [1 ]
机构
[1] Konkuk Univ, Div Biosci & Biotechnol, Seoul 143701, South Korea
[2] Konkuk Univ, Dept Environm Sci, Seoul 143701, South Korea
[3] Chung Ang Univ, Dept Food Sci & Technol, Anseong 456756, South Korea
[4] Konkuk Univ, Biomol Informat Ctr, Seoul 143701, South Korea
关键词
ethyl carbamate; average daily intake; excess cancer risk; risk assessment;
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Levels of ethyl carbamate, a potential carcinogen produced naturally during fermentation, in major Korean fermented foods and alcoholic beverages were determined by GC/MS/SIM, and their average daily intake and excess cancer risk in Korean people were estimated. In GC/MS/SIM analysis n.d.-4.26, 1.40-58.90, n.d.-3.76, n.d.-1.87, and 0.40-10.07 mu g/kg of ethyl carbamate were detected in kimchi, soy sauces, fermented pastes, fermented dairy products, and alcoholic beverages, respectively. The average daily intake of ethyl carbamate and excess cancer risk through major Korean fermented foods and alcoholic beverage consumption were 6.0 ng/kg bw/day and 3.0 x 10(-7), respectively for the average Korean person aged 3-64 years, and were mainly contributed by Chinese cabbage kimchi, soy sauces, and Soju.
引用
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页码:1961 / 1967
页数:7
相关论文
共 34 条
  • [1] Arginine, citrulline and ornithine metabolism by lactic acid bacteria from wine
    Arena, ME
    Saguir, FM
    de Nadra, MCM
    [J]. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 1999, 52 (03) : 155 - 161
  • [2] Copper(II) catalysis in cyanide conversion into ethyl carbamate in spirits and relevant reactions
    Aresta, M
    Boscolo, M
    Franco, DW
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2001, 49 (06) : 2819 - 2824
  • [3] ETHYL CARBAMATE (URETHANE) IN ALCOHOLIC BEVERAGES AND FOODS - A REVIEW
    BATTAGLIA, R
    CONACHER, HBS
    PAGE, BD
    [J]. FOOD ADDITIVES AND CONTAMINANTS, 1990, 7 (04): : 477 - 496
  • [4] Effect of ethanol on the tumorigenicity of urethane (ethyl carbamate) in B6C3F1 mice
    Beland, FA
    Benson, RW
    Mellick, PW
    Kovatch, RM
    Roberts, DW
    Fang, JL
    Doerge, DR
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2005, 43 (01) : 1 - 19
  • [5] Modulation of urethane (ethyl carbamate) carcinogenicity by ethyl alcohol: A review
    Benson, RW
    Beland, FA
    [J]. INTERNATIONAL JOURNAL OF TOXICOLOGY, 1997, 16 (06) : 521 - 544
  • [6] CANAS BJ, 1989, J ASSOC OFF ANA CHEM, V72, P873
  • [7] Role of corticosterone in ethyl carbamate-induced Immunosuppression in female BALB/c mice
    Cha, SW
    Lee, HJ
    Cho, MH
    Lee, MH
    Koh, WS
    Han, SS
    Kim, JA
    Lee, ES
    Nam, DH
    Jeong, TC
    [J]. TOXICOLOGY LETTERS, 2001, 119 (03) : 173 - 181
  • [8] CHUNG HJ, 1997, KOREAN J SOC FOOD SC, V13, P92
  • [9] CONACHER HBS, 1987, J ASSOC OFF ANA CHEM, V70, P749
  • [10] DEORDUNA RM, 2000, FEMS MICROBIOL LETT, V183, P31, DOI DOI 10.1016/S0378-1097(99)00624-2