Single and Mitochondrial Gene Inheritance Disorder Prediction Using Machine Learning

被引:9
作者
Nasir, Muhammad Umar [1 ]
Khan, Muhammad Adnan [1 ,2 ]
Zubair, Muhammad [3 ]
Ghazal, Taher M. [4 ,5 ]
Said, Raed A. [6 ]
Al Hamadi, Hussam [7 ]
机构
[1] Riphah Int Univ, Fac Comp, Riphah Sch Comp & Innovat, Lahore Campus, Lahore 54000, Pakistan
[2] Gachon Univ, Dept Software, Pattern Recognit & Machine Learning Lab, Seongnam 13120, Gyeonggido, South Korea
[3] Riphah Int Univ, Fac Comp, Islamabad 45000, Pakistan
[4] Skyline Univ Coll, Sch Informat Technol, Sharjah 1797, U Arab Emirates
[5] Univ Kebangsaan Malaysia, Fac Informat Sci & Technol, Ctr Cyber Secur, Network & Commun Technol Lab, Bangi 43600, Malaysia
[6] Canadian Univ, Dubai 00000, U Arab Emirates
[7] Khalifa Univ, Cyber Phys Syst, Abu Dhabi 127788, U Arab Emirates
来源
CMC-COMPUTERS MATERIALS & CONTINUA | 2022年 / 73卷 / 01期
关键词
Genetic disorder; machine learning; deep learning; single gene inheritance gene disorder; mitochondrial gene inheritance disorder;
D O I
10.32604/cmc.2022.028958
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
One of the most difficult jobs in the post-genomic age is identifying a genetic disease from a massive amount of genetic data. Furthermore, the complicated genetic disease has a very diverse genotype, making it challenging to find genetic markers. This is a challenging process since it must be completed effectively and efficiently. This research article focuses largely on which patients are more likely to have a genetic disorder based on numerous medical parameters. Using the patient???s medical history, we used a genetic disease prediction algorithm that predicts if the patient is likely to be diagnosed with a genetic disorder. To predict and categorize the patient with a genetic disease, we utilize several deep and machine learning techniques such as Artificial neural network (ANN), K-nearest neighbors (KNN), and Support vector machine (SVM). To enhance the accuracy of predicting the genetic disease in any patient, a highly efficient approach was utilized to control how the model can be used. To predict genetic disease, deep and machine learning approaches are performed. The most productive tool model provides more precise efficiency. The simulation results demonstrate that by using the proposed model with the ANN, we achieve the highest model performance of 85.7%, 84.9%, 84.3% accuracy of training, testing and validation respectively. give a real competitive strategy to save patients??? lives.
引用
收藏
页码:953 / 963
页数:11
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